American Journal of Psychiatry
- Volume 172
- Number 4
- April 2015
Perspectives
Editorials
Perspectives
Commentary
Perspectives
Education in Psychiatry
Publication date: 31 March 2015
Pages316–320Objective:The limitations of the DSM nosology for capturing dimensionality and overlap in psychiatric syndromes, and its poor correspondence to underlying neurobiology, have been well established. The Research Domain Criteria (RDoC), a proposed ...
https://doi.org/10.1176/appi.ajp.2014.14091177Perspectives
Images in Psychiatry
Perspectives
Reviews and Overviews
Publication date: 20 February 2015
Pages323–334Objective:Public health campaigns encouraging early help seeking have increased rates of mild cognitive impairment (MCI) diagnosis in Western countries, but we know little about how to treat or predict dementia outcomes in persons with the condition....
https://doi.org/10.1176/appi.ajp.2014.14070878New Research
Articles
Publication date: 19 December 2014
Pages335–343Objective:In alcohol-dependent patients, alcohol cues evoke increased activation in mesolimbic brain areas, such as the nucleus accumbens and the amygdala. Moreover, patients show an alcohol approach bias, a tendency to more quickly approach than avoid ...
https://doi.org/10.1176/appi.ajp.2014.13111495Publication date: 12 December 2014
Pages344–352Objective:Few studies targeting obesity in serious mental illness have reported clinically significant risk reduction, and none have been replicated in community settings or demonstrated sustained outcomes after intervention withdrawal. The authors sought ...
https://doi.org/10.1176/appi.ajp.2014.14030357Publication date: 12 December 2014
Pages353–362Objective:Increased systemic inflammation is associated with stress-related psychopathology. Specifically, levels of the proinflammatory marker C-reactive protein (CRP) are elevated in individuals with posttraumatic stress disorder (PTSD). Furthermore, ...
https://doi.org/10.1176/appi.ajp.2014.14020263Publication date: 12 December 2014
Pages363–372Objective:The study was designed to validate use of electronic health records (EHRs) for diagnosing bipolar disorder and classifying control subjects.Method:EHR data were obtained from a health care system of more than 4.6 million patients spanning more ...
https://doi.org/10.1176/appi.ajp.2014.14030423Publication date: 13 January 2015
Pages373–382Objective:In schizophrenia, hippocampal perfusion is increased and declarative memory function is degraded. Based on an a priori model of hippocampal dysfunction in schizophrenic psychosis, the authors postulated molecular and cellular changes in CA3 ...
https://doi.org/10.1176/appi.ajp.2014.14010123Publication date: 19 December 2014
Pages383–392Objective:The authors assessed the functioning of mesolimbic and striatal areas involved in reward-based spatial learning in unmedicated adults with obsessive-compulsive disorder (OCD).Method:Functional MRI blood-oxygen-level-dependent response was ...
https://doi.org/10.1176/appi.ajp.2014.13121700Communications and Updates
Letters to the Editor
Disclosure of Editors’ Financial Relationships
Past Issues
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