American Journal of Psychiatry
- Volume 172
- Number 3
- March 2015
Perspectives
Editorials
Perspectives
Clinical Case Conference
Perspectives
Perspectives in Global Mental Health
Perspectives
Images in Psychiatry
Perspectives
Reviews and Overviews
Publication date: 13 January 2015
Pages227–236Objective: In this conceptual review, the authors propose a novel mechanistic candidate in the etiology of depression with onset in the menopause transition (“perimenopausal depression”) involving alterations in stress-responsive pathways, induced by ...
https://doi.org/10.1176/appi.ajp.2014.14070918New Research
Articles
Publication date: 04 December 2014
Pages237–248Objective: Treatment guidelines suggest distinctive medication strategies for first-episode and multiepisode patients with schizophrenia. To assess the extent to which community clinicians adjust their usual treatment regimens for first-episode patients, ...
https://doi.org/10.1176/appi.ajp.2014.13101355Publication date: 01 March 2015
Pages249–258Objective: Two-thirds of individuals identified as at ultra-high risk for psychosis do not develop psychotic disorder over the medium term. The authors examined outcomes in a group of such patients. Method: Participants were help-seeking individuals ...
https://doi.org/10.1176/appi.ajp.2014.13030418Publication date: 01 March 2015
Pages259–265Objective: The authors sought to clarify the relationship between IQ and subsequent risk for schizophrenia. Method: IQ was assessed at ages 18–20 in 1,204,983 Swedish males born between 1951 and 1975. Schizophrenia was assessed by hospital diagnosis through ...
https://doi.org/10.1176/appi.ajp.2014.14040516Publication date: 01 March 2015
Pages266–275Objective: Autism spectrum disorder is characterized by deficits in social function and the presence of repetitive and restrictive behaviors. Following a previous test of principle, the authors adopted a quantitative approach to discovering genes ...
https://doi.org/10.1176/appi.ajp.2014.14050576Publication date: 19 December 2014
Pages276–283Objective: Although heightened amygdala reactivity is observed in patients with major depression, two critical gaps in our knowledge remain. First, it is unclear whether heightened amygdala reactivity is a premorbid vulnerability or a consequence of the ...
https://doi.org/10.1176/appi.ajp.2014.14020195Publication date: 19 December 2014
Pages284–293Objective: The purpose of this study was to determine the neural correlates of excessive habit formation in obsessive-compulsive disorder (OCD). The authors aimed to test for neurobiological convergence with the known pathophysiology of OCD and to infer, ...
https://doi.org/10.1176/appi.ajp.2014.14040525