American Journal of Psychiatry

Postpartum psychosis is a severe disorder that warrants acute clinical intervention. Little is known, however, about what interventions are most effective. The authors present treatment response and remission outcomes at 9 months postpartum using a four-...

https://doi.org/10.1176/appi.ajp.2014.13121652

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Perspectives

Reviews and Overviews

Identifying Predictors, Moderators, and Mediators of Antidepressant Response in Major Depressive Disorder: Neuroimaging Approaches

Publication date: 01 February 2015

Pages124–138

Objective: Despite significant advances in neuroscience and treatment development, no widely accepted biomarkers are available to inform diagnostics or identify preferred treatments for individuals with major depressive disorder. Method: In this critical ...

https://doi.org/10.1176/appi.ajp.2014.14010076

New Research

Articles

Uncovering the Hidden Risk Architecture of the Schizophrenias: Confirmation in Three Independent Genome-Wide Association Studies

Publication date: 01 February 2015

Pages139–153

Objective: The authors sought to demonstrate that schizophrenia is a heterogeneous group of heritable disorders caused by different genotypic networks that cause distinct clinical syndromes. Method: In a large genome-wide association study of cases with ...

https://doi.org/10.1176/appi.ajp.2014.14040435

Paraprofessional-Delivered Home-Visiting Intervention for American Indian Teen Mothers and Children: 3-Year Outcomes From a Randomized Controlled Trial

Publication date: 01 February 2015

Pages154–162

Objective: The Affordable Care Act provides funding for home-visiting programs to reduce health care disparities, despite limited evidence that existing programs can overcome implementation and evaluation challenges with at-risk populations. The authors ...

https://doi.org/10.1176/appi.ajp.2014.14030332

COMT Haplotypes Modulate Associations of Antenatal Maternal Anxiety and Neonatal Cortical Morphology

Publication date: 01 February 2015

Pages163–172

Objective: Exposure to antenatal maternal anxiety and complex genetic variations may shape fetal brain development. In particular, the catechol-O-methyltransferase (COMT) gene, located on chromosome 22q11.2, regulates catecholamine signaling in the ...

https://doi.org/10.1176/appi.ajp.2014.14030313

Feedback-Driven Trial-by-Trial Learning in Autism Spectrum Disorders

Publication date: 01 February 2015

Pages173–181

Objective: Impairments in learning are central to autism spectrum disorders. The authors investigated the cognitive and neural basis of these deficits in young adults with autism spectrum disorders using a well-characterized probabilistic reinforcement ...

https://doi.org/10.1176/appi.ajp.2014.14010036

Effect of the Affordable Care Act’s Young Adult Insurance Expansions on Hospital-Based Mental Health Care

Publication date: 01 February 2015

Pages182–189

Objective: Insurance coverage for young adults has increased since 2010, when the Affordable Care Act (ACA) required insurers to permit children to remain on parental policies until age 26 as dependents. This study estimated the association between the ...

https://doi.org/10.1176/appi.ajp.2014.14030375

Pleiotropic Locus for Emotion Recognition and Amygdala Volume Identified Using Univariate and Bivariate Linkage

Publication date: 01 February 2015

Pages190–199

Objective: The role of the amygdala in emotion recognition is well established, and amygdala volume and emotion recognition performance have each been shown separately to be highly heritable traits, but the potential role of common genetic influences on ...

https://doi.org/10.1176/appi.ajp.2014.14030311