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Published Online: 20 June 2018

The Burden of Bereavement: Early-Onset Depression and Impairment in Youths Bereaved by Sudden Parental Death in a 7-Year Prospective Study

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Abstract

Objective:

The authors sought to determine the long-term impact of sudden parental death on youths and pathways between youth bereavement and impairment.

Methods:

Youths (N=216) who lost a parent to suicide, accident, or sudden natural death and nonbereaved youths (N=172) were followed periodically for up to 7 years. The incidence and prevalence of disorder and of functional impairment, as well as pathways to impairment, were assessed using Cox and mixed-effects logistic regression and structural equation modeling.

Results:

Prior to parental death, bereaved youths had higher rates of psychiatric disorder, parental psychiatric disorder, and maltreatment. Even after adjustment for predeath risk factors, bereavement was associated with an increased incidence of depression, posttraumatic stress disorder, and functional impairment. The peak incidence of depression was in the first 2 years postbereavement, with incident depression occurring mainly in those who lost a parent at age 12 or younger. Youths bereaved by all three causes of death showed higher rates of impairment at all time points. Structural equation modeling found that bereavement had a direct effect on impairment and was also linked to impairment via its effects on early and later depression and through negative life events. Child psychiatric disorder prior to parental loss also contributed to functional impairment.

Conclusions:

Parental death increased the incidence of depression in offspring early in the course of bereavement. Early identification and treatment of depression in bereaved youths and augmentation of family resilience may protect against later sequelae of functional impairment.

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Information & Authors

Information

Published In

Go to American Journal of Psychiatry
Go to American Journal of Psychiatry
American Journal of Psychiatry
Pages: 887 - 896
PubMed: 29921145

History

Received: 18 July 2017
Revision received: 15 November 2017
Revision received: 14 February 2018
Revision received: 1 March 2018
Accepted: 5 March 2018
Published online: 20 June 2018
Published in print: September 01, 2018

Keywords

  1. Parental Bereavement
  2. Sudden Death
  3. Depression
  4. PTSD
  5. Functional Impairment

Authors

Affiliations

Steven Pham, M.D.
From the Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh; Cincinnati Children’s Hospital Medical Center, Cincinnati; the Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati; the Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh; and the Department of Statistics, University of Pittsburgh, Pittsburgh.
Giovanna Porta, M.S.
From the Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh; Cincinnati Children’s Hospital Medical Center, Cincinnati; the Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati; the Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh; and the Department of Statistics, University of Pittsburgh, Pittsburgh.
Candice Biernesser, L.C.S.W., M.P.H.
From the Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh; Cincinnati Children’s Hospital Medical Center, Cincinnati; the Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati; the Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh; and the Department of Statistics, University of Pittsburgh, Pittsburgh.
Monica Walker Payne, M.A.
From the Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh; Cincinnati Children’s Hospital Medical Center, Cincinnati; the Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati; the Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh; and the Department of Statistics, University of Pittsburgh, Pittsburgh.
Satish Iyengar, Ph.D.
From the Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh; Cincinnati Children’s Hospital Medical Center, Cincinnati; the Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati; the Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh; and the Department of Statistics, University of Pittsburgh, Pittsburgh.
Nadine Melhem, Ph.D.
From the Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh; Cincinnati Children’s Hospital Medical Center, Cincinnati; the Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati; the Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh; and the Department of Statistics, University of Pittsburgh, Pittsburgh.
David A. Brent, M.D. [email protected]
From the Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh; Cincinnati Children’s Hospital Medical Center, Cincinnati; the Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati; the Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh; and the Department of Statistics, University of Pittsburgh, Pittsburgh.

Notes

Address correspondence to Dr. Brent ([email protected]).

Funding Information

American Foundation for Suicide Prevention10.13039/100001455: Young Investigator Award
National Institute of Mental Health10.13039/100000025: MH018951, MH065368
University of Pittsburgh Clinical Scientist Training Program from the Clinical and Translation Science Institute grant: UL1TR001857
Supported by NIMH grants MH-065368 to Dr. Brent and MH-018951 to Dr. Pham, by an American Foundation for Suicide Prevention Young Investigator Award to Dr. Melhem, and by grant UL1TR001857 from the University of Pittsburgh Clinical Scientist Training Program from the Clinical and Translational Science Institute to Dr. Pham.Dr. Brent receives royalties from Guilford Press, has received or will receive royalties from the electronic self-rated version of the Columbia–Suicide Severity Rating Scale from eResearch Technology, is on the editorial board of UpToDate, is a reviewer for Healthwise, and is a consultant for McKesson. The other authors report no financial relationships with commercial interests.

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