When Discontinuing SSRI Antidepressants Is a Challenge: Management Tips

Supported through the Center for Depression Research and Clinical Care (principal investigator, Dr. Trivedi) and the Hersh Foundation.Dr. Jha has received contract research funding from Acadia Pharmaceuticals and Janssen Research. Dr. Rush has received consulting fees from Akili, Brain Resource, Compass, Curbstone Consultant, Eli Lilly, the Emmes Corporation, Johnson & Johnson (Janssen), LivaNova, MindLinc, Sunovion, Takeda USA, and Taj Medical; he has received speaking fees from LivaNova and royalties from Guilford Press and the University of Texas Southwestern Medical Center, Dallas (for the Inventory of Depressive Symptoms and its derivatives); and he is named co-inventor on two patents (7,795,033 and 7,906,283, on methods to predict outcome and risk of side effects with antidepressant treatment). Dr. Trivedi has served as a consultant or on advisory boards for Alkermes, Akili Interactive, Allergan Pharmaceuticals, Acadia Pharmaceuticals, Avanir Pharmaceuticals, Brintellix Global, Bristol-Myers Squibb, Caudex, Cerecor, Forest Pharmaceuticals, Global Medical Education, Health Research Associates, Insys, Johnson & Johnson Pharmaceutical Research and Development, Lilly Research Laboratories, Lundbeck Research USA, Medscape, Merck, Mitsubishi Pharma, MSI Methylation Sciences–Pamlab, Navitor, One Carbon Therapeutics, Otsuka America Pharmaceutical, Pfizer, and Takeda Global Research; he has received royalties from Janssen Research and Development; he has author agreements from Janssen Asia Pacific and Oxford University Press; and he has received grants from the Agency for Healthcare Research and Quality, the Cancer Prevention and Research Institute of Texas, the National Institute of Diabetes and Digestive and Kidney Diseases, the National Center for Advancing Translational Sciences, NIMH, NIDA, Johnson & Johnson, and the Patient-Centered Outcomes Research Institute.