American Journal of Psychiatry
- Volume 175
- Number 12
- December 2018
Editor’s Note
Editorials
Introspection
Treatment in Psychiatry
Images in Psychiatry
Reviews and Overviews
Publication date: 17 September 2018
Pages1187–1198Specific challenges that profoundly affect the outcome of treatment for depression include 1) patient engagement and retention in care and optimization of treatment adherence, 2) optimization of symptom and side effect control by medication adjustments ...
https://doi.org/10.1176/appi.ajp.2018.18040398Publication date: 25 April 2018
Pages1199–1204The authors trace the modern history, current landscape, and future prospects for integration between mental health and general medical care in the United States. Research and new treatment models developed in the 1980s and early 1990s helped inform ...
https://doi.org/10.1176/appi.ajp.2018.18020169Articles
Publication date: 29 August 2018
Pages1205–1215Objective: In addition to N-methyl-d-aspartate receptor antagonism, ketamine produces opioid system activation. The objective of this study was to determine whether opioid receptor antagonism prior to administration of intravenous ketamine attenuates its ...
https://doi.org/10.1176/appi.ajp.2018.18020138Publication date: 29 August 2018
Pages1216–1224Objective: Current medications for alcohol use disorder do not target brain noradrenergic pathways. Theoretical and preclinical evidence suggests that noradrenergic circuits may be involved in alcohol reinforcement and relapse. After a positive pilot study,...
https://doi.org/10.1176/appi.ajp.2018.17080913Publication date: 16 August 2018
Pages1225–1231Objective: Second-generation antipsychotics are commonly prescribed to reproductive-age women for the treatment of a spectrum of psychiatric disorders. Quetiapine is the most commonly prescribed medication in this class, and therefore a better ...
https://doi.org/10.1176/appi.ajp.2018.18010098Publication date: 03 October 2018
Pages1232–1242Objective: Children of mothers with severe mental illness are at significantly increased risk of developing intellectual disability. Obstetric complications are also implicated in the risk for intellectual disability. Moreover, children of mothers with ...
https://doi.org/10.1176/appi.ajp.2018.17101153Publication date: 03 October 2018
Pages1243–1254Objective: The ability to perceive the motion of biological objects, such as faces, is a critical component of daily function and correlates with the ability to successfully navigate social situations (social cognition). Deficits in motion perception in ...
https://doi.org/10.1176/appi.ajp.2018.18010072Publication date: 16 August 2018
Pages1255–1264Objective: White matter microstructure alterations have recently been associated with depressive episodes during adolescence, but it is unknown whether they predate depression. The authors investigated whether subthreshold depression in adolescence is ...
https://doi.org/10.1176/appi.ajp.2018.17070825Letters to the Editor
Book Forum
Appreciation
Publication date: 01 December 2018
Pages1274–1278https://doi.org/10.1176/appi.ajp.2018.17512reviewers