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American Journal of Psychiatry

  • Volume 175
  • Number 12
  • December 2018

Editor’s Note

Editorials

Introspection

Treatment in Psychiatry

Images in Psychiatry

Reviews and Overviews

Publication date: 17 September 2018

Pages1187–1198

Specific challenges that profoundly affect the outcome of treatment for depression include 1) patient engagement and retention in care and optimization of treatment adherence, 2) optimization of symptom and side effect control by medication adjustments ...

https://doi.org/10.1176/appi.ajp.2018.18040398

Publication date: 25 April 2018

Pages1199–1204

The authors trace the modern history, current landscape, and future prospects for integration between mental health and general medical care in the United States. Research and new treatment models developed in the 1980s and early 1990s helped inform ...

https://doi.org/10.1176/appi.ajp.2018.18020169

Articles

Publication date: 29 August 2018

Pages1205–1215

Objective: In addition to N-methyl-d-aspartate receptor antagonism, ketamine produces opioid system activation. The objective of this study was to determine whether opioid receptor antagonism prior to administration of intravenous ketamine attenuates its ...

https://doi.org/10.1176/appi.ajp.2018.18020138

Publication date: 29 August 2018

Pages1216–1224

Objective: Current medications for alcohol use disorder do not target brain noradrenergic pathways. Theoretical and preclinical evidence suggests that noradrenergic circuits may be involved in alcohol reinforcement and relapse. After a positive pilot study,...

https://doi.org/10.1176/appi.ajp.2018.17080913

Publication date: 16 August 2018

Pages1225–1231

Objective: Second-generation antipsychotics are commonly prescribed to reproductive-age women for the treatment of a spectrum of psychiatric disorders. Quetiapine is the most commonly prescribed medication in this class, and therefore a better ...

https://doi.org/10.1176/appi.ajp.2018.18010098

Publication date: 03 October 2018

Pages1232–1242

Objective: Children of mothers with severe mental illness are at significantly increased risk of developing intellectual disability. Obstetric complications are also implicated in the risk for intellectual disability. Moreover, children of mothers with ...

https://doi.org/10.1176/appi.ajp.2018.17101153

Publication date: 03 October 2018

Pages1243–1254

Objective: The ability to perceive the motion of biological objects, such as faces, is a critical component of daily function and correlates with the ability to successfully navigate social situations (social cognition). Deficits in motion perception in ...

https://doi.org/10.1176/appi.ajp.2018.18010072

Publication date: 16 August 2018

Pages1255–1264

Objective: White matter microstructure alterations have recently been associated with depressive episodes during adolescence, but it is unknown whether they predate depression. The authors investigated whether subthreshold depression in adolescence is ...

https://doi.org/10.1176/appi.ajp.2018.17070825

Letters to the Editor

Book Forum

Appreciation

Past Issues

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No.11
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1 Nov 2024

Vol. 181 | No. 11

No.10
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1 Oct 2024

Vol. 181 | No. 10

No.9
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1 Sep 2024

Vol. 181 | No. 9

No.8
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1 Aug 2024

Vol. 181 | No. 8