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Abstract

Trichotillomania (hair pulling disorder) and skin-picking (excoriation) disorder are common neuropsychiatric disorders (each with a point prevalence of around 2%) but are underrecognized by professionals. Affected individuals repeatedly pull out their own hair or pick at their skin, and these symptoms not only have a negative impact on these individuals because of the time they occupy but can also lead to considerable physical disfigurement, with concomitant loss of self-esteem and avoidance of social activities and intimate relationships. The behaviors may also have serious physical consequences. Trichotillomania and skin picking frequently co-occur, and both disorders commonly present with co-occurring depression, anxiety, impulsive, and obsessive-compulsive disorders. Behavioral therapy currently appears to be the most effective treatment for both. Pharmacotherapy, in the form of N-acetylcysteine or olanzapine, may also play a role in treatment.

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History

Published in print: Fall 2021
Published online: 5 November 2021

Keywords

  1. Obsessive-Compulsive Disorder - AJP0019trichotillomania
  2. skin picking disorder
  3. treatment
  4. phenomenology

Authors

Affiliations

Jon E. Grant, J.D., M.D., M.P.H. [email protected]
Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago (Grant); Department of Psychiatry, Faculty of Medicine, University of Southampton, and Southern Health NHS Foundation Trust, both in Southampton, United Kingdom (Chamberlain).
Samuel R. Chamberlain, M.D., Ph.D.
Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago (Grant); Department of Psychiatry, Faculty of Medicine, University of Southampton, and Southern Health NHS Foundation Trust, both in Southampton, United Kingdom (Chamberlain).

Notes

Send correspondence to Dr. Grant ([email protected]).

Competing Interests

Dr. Grant has received research grants from Otsuka, Roche, and Promentis Pharmaceuticals; receives yearly compensation from Springer Publishing for acting as Editor-in-Chief of the Journal of Gambling Studies; and has received royalties from Oxford University Press, American Psychiatric Publishing, Inc., Norton Press, and McGraw Hill. Dr. Chamberlain previously consulted for Promentis and receives honoraria from Elsevier for editorial work for Comprehensive Psychiatry and Neuroscience and Biobehavioral Reviews.

Funding Information

Dr. Chamberlain’s role in this work was funded by a Wellcome Trust Clinical Fellowship (110049/Z/15/Z and 110049/Z/15/A).

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