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Published Online: 1 January 2012

Getting Past “g”: Testing a New Model of Dementing Processes in Persons Without Dementia

Publication: The Journal of Neuropsychiatry and Clinical Neurosciences

Abstract

The cognitive correlates of functional status are essential to dementia case-finding. The authors have used structural-equation models to explicitly distinguish dementia-relevant variance in cognitive task performance (i.e., δ) from the variance that is unrelated to a dementing process (i.e., g′). Together, g′ and δ comprise Spearman's “g.” Although δ represents only a small fraction of the total variance in cognitive task performance, it is more strongly associated with dementia severity than is g′. In this analysis, the authors test whether δ can predict future cognitive decline in persons clinically without dementia at baseline. These results have implications for the clinical assessment of dementia and suggest that functional status should assume a more important role.

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Published In

Go to The Journal of Neuropsychiatry and Clinical Neurosciences
Go to The Journal of Neuropsychiatry and Clinical Neurosciences
The Journal of Neuropsychiatry and Clinical Neurosciences
Pages: 37 - 46
PubMed: 22450612

History

Received: 1 April 2011
Accepted: 6 July 2011
Published online: 1 January 2012
Published in print: Winter 2012

Keywords

  1. Aging
  2. Cognition
  3. Dementia
  4. “g,”
  5. Functional Status

Authors

Details

Donald R. Royall, M.D.
From the Departments of Psychiatry (DRR); Medicine (DRR); and Family and Community Medicine (DRR, RFP); the University of Texas Health Science Center, San Antonio, TX; and the South Texas Veterans' Health System Audie L. Murphy Division, GRECC (DRR).
Raymond F. Palmer, Ph.D.
From the Departments of Psychiatry (DRR); Medicine (DRR); and Family and Community Medicine (DRR, RFP); the University of Texas Health Science Center, San Antonio, TX; and the South Texas Veterans' Health System Audie L. Murphy Division, GRECC (DRR).

Notes

Correspondence: Donald R. Royall, M.D.; [email protected] (e-mail).

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