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Published Online: 1 January 2014

Comparison of Cognitive Functioning Among Individuals With Treated Restless Legs Syndrome (RLS), Untreated RLS, and No RLS

Hochang Benjamin Lee, M.D., Christine M. Ramsey, B.S., Adam P. Spira, Ph.D., Jacqueline Vachon, M.S., Richard Allen, Ph.D., and Cynthia A. Munro, Ph.D.Authors Info & Affiliations
Publication: The Journal of Neuropsychiatry and Clinical Neurosciences
Volume 26, Number 1
https://doi.org/10.1176/appi.neuropsych.12120394
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Abstract

Restless legs syndrome (RLS) is a common neurological sensory-motor condition. High prevalence of comorbid depression and anxiety has been reported, but the few available data on the impact of RLS on cognition have been conflicting. The authors compared 91 participants (No-RLS group: N=37; Untreated RLS group: N=23; Treated RLS group: N=31) on cognitive performance and depression ratings. There were minimal observed group differences in cognitive performance, but the untreated RLS group had significantly higher depressive symptoms than the treated RLS and the no-RLS groups. RLS does not appear to affect cognition, but there does appear to be a strong association between untreated RLS and depression.

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Published In

Go to The Journal of Neuropsychiatry and Clinical Neurosciences
Go to The Journal of Neuropsychiatry and Clinical Neurosciences
The Journal of Neuropsychiatry and Clinical Neurosciences
Volume 26 • Number 1 • Winter 2014
Pages: 87 - 91
PubMed: 24515680

History

Received: 7 December 2012
Revision received: 18 March 2013
Revision received: 5 April 2013
Accepted: 14 May 2013
Published online: 1 January 2014
Published in print: Winter 2014

Authors

Details

Hochang Benjamin Lee, M.D.
From the Dept. of Psychiatry at Yale University, New Haven, CT; Dept. of Mental Health, Johns Hopkins Bloomberg School of Public Health; Depts. of Neurology and Psychiatry and Behavioral Sciences at the Johns Hopkins University School of Medicine, Baltimore, MD.
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Christine M. Ramsey, B.S.
From the Dept. of Psychiatry at Yale University, New Haven, CT; Dept. of Mental Health, Johns Hopkins Bloomberg School of Public Health; Depts. of Neurology and Psychiatry and Behavioral Sciences at the Johns Hopkins University School of Medicine, Baltimore, MD.
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Adam P. Spira, Ph.D.
From the Dept. of Psychiatry at Yale University, New Haven, CT; Dept. of Mental Health, Johns Hopkins Bloomberg School of Public Health; Depts. of Neurology and Psychiatry and Behavioral Sciences at the Johns Hopkins University School of Medicine, Baltimore, MD.
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Jacqueline Vachon, M.S.
From the Dept. of Psychiatry at Yale University, New Haven, CT; Dept. of Mental Health, Johns Hopkins Bloomberg School of Public Health; Depts. of Neurology and Psychiatry and Behavioral Sciences at the Johns Hopkins University School of Medicine, Baltimore, MD.
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Richard Allen, Ph.D.
From the Dept. of Psychiatry at Yale University, New Haven, CT; Dept. of Mental Health, Johns Hopkins Bloomberg School of Public Health; Depts. of Neurology and Psychiatry and Behavioral Sciences at the Johns Hopkins University School of Medicine, Baltimore, MD.
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Cynthia A. Munro, Ph.D.
From the Dept. of Psychiatry at Yale University, New Haven, CT; Dept. of Mental Health, Johns Hopkins Bloomberg School of Public Health; Depts. of Neurology and Psychiatry and Behavioral Sciences at the Johns Hopkins University School of Medicine, Baltimore, MD.
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Notes

Send correspondence to Hochang Benjamin Lee, M.D.; e-mail: [email protected]

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