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Abstract

Objective:

Persons with serious mental illness have an increased mortality rate and a higher burden of many medical conditions compared with persons without serious mental illness. Cancer risk in the population with serious mental illness is uncertain, and its incidence was examined by race, sex, and cancer site in a community-based cohort of adults with schizophrenia or bipolar disorder.

Methods:

The authors calculated standardized incidence ratios of total and site-specific cancers in a cohort of 3,317 Maryland Medicaid adult beneficiaries with schizophrenia or bipolar disorder followed from 1994 through2004 for comparison with the U.S. population.

Results:

Total cancer incidence for adults with schizophrenia or bipolar disorder was 2.6 times higher in the cohort. Elevated risk was greatest for cancer of the lung. No differences in risk were found for African-American versus white Medicaid beneficiaries with serious mental illness.

Conclusions:

These findings suggest that there is a heightened risk of cancer among adults with schizophrenia or bipolar disorder. Clinicians should promote appropriate cancer screening and work to reduce modifiable risk factors, such as smoking, among persons with serious mental illness. (Psychiatric Services 63:714–717, 2012; doi: 10.1176/appi.ps.201100169)

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Table 1 Cancer statistics for a cohort of 3,317 Maryland Medicaid beneficiaries with schizophrenia or bipolar disorder and for the general population

Information & Authors

Information

Published In

Go to Psychiatric Services
Go to Psychiatric Services
Cover: Flag on Orange Field, by Jasper Johns, 1967. Museum Ludwig, Cologne, Germany. © VAGA, New York. Photo © Erich Lessing/Art Resource, New York.
Psychiatric Services
Pages: 714 - 717
PubMed: 22752037

History

Published online: 1 July 2012
Published in print: July 2012

Authors

Details

Emma Elizabeth McGinty, M.S.
Ms. McGinty and Dr. Steinwachs are affiliated with the Department of Health Policy and Management and Dr. Zhang and Dr. Guallar are with the Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore. Dr. Ford and Dr. Daumit are with the Division of General Internal Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore. Dr. Dixon is with the Department of Psychiatry, University of Maryland School of Medicine, Baltimore. Dr. Keating is with the Department of Health Care Policy, Harvard Medical School, Boston.
Yiyi Zhang, Ph.D.
Ms. McGinty and Dr. Steinwachs are affiliated with the Department of Health Policy and Management and Dr. Zhang and Dr. Guallar are with the Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore. Dr. Ford and Dr. Daumit are with the Division of General Internal Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore. Dr. Dixon is with the Department of Psychiatry, University of Maryland School of Medicine, Baltimore. Dr. Keating is with the Department of Health Care Policy, Harvard Medical School, Boston.
Eliseo Guallar, M.D., Dr.P.H.
Ms. McGinty and Dr. Steinwachs are affiliated with the Department of Health Policy and Management and Dr. Zhang and Dr. Guallar are with the Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore. Dr. Ford and Dr. Daumit are with the Division of General Internal Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore. Dr. Dixon is with the Department of Psychiatry, University of Maryland School of Medicine, Baltimore. Dr. Keating is with the Department of Health Care Policy, Harvard Medical School, Boston.
Daniel E. Ford, M.D., M.P.H.
Ms. McGinty and Dr. Steinwachs are affiliated with the Department of Health Policy and Management and Dr. Zhang and Dr. Guallar are with the Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore. Dr. Ford and Dr. Daumit are with the Division of General Internal Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore. Dr. Dixon is with the Department of Psychiatry, University of Maryland School of Medicine, Baltimore. Dr. Keating is with the Department of Health Care Policy, Harvard Medical School, Boston.
Donald Steinwachs, Ph.D.
Ms. McGinty and Dr. Steinwachs are affiliated with the Department of Health Policy and Management and Dr. Zhang and Dr. Guallar are with the Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore. Dr. Ford and Dr. Daumit are with the Division of General Internal Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore. Dr. Dixon is with the Department of Psychiatry, University of Maryland School of Medicine, Baltimore. Dr. Keating is with the Department of Health Care Policy, Harvard Medical School, Boston.
Lisa B. Dixon, M.D., M.P.H.
Ms. McGinty and Dr. Steinwachs are affiliated with the Department of Health Policy and Management and Dr. Zhang and Dr. Guallar are with the Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore. Dr. Ford and Dr. Daumit are with the Division of General Internal Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore. Dr. Dixon is with the Department of Psychiatry, University of Maryland School of Medicine, Baltimore. Dr. Keating is with the Department of Health Care Policy, Harvard Medical School, Boston.
Nancy L. Keating, M.D., M.P.H.
Ms. McGinty and Dr. Steinwachs are affiliated with the Department of Health Policy and Management and Dr. Zhang and Dr. Guallar are with the Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore. Dr. Ford and Dr. Daumit are with the Division of General Internal Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore. Dr. Dixon is with the Department of Psychiatry, University of Maryland School of Medicine, Baltimore. Dr. Keating is with the Department of Health Care Policy, Harvard Medical School, Boston.
Gail L. Daumit, M.D., M.H.S.
Ms. McGinty and Dr. Steinwachs are affiliated with the Department of Health Policy and Management and Dr. Zhang and Dr. Guallar are with the Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore. Dr. Ford and Dr. Daumit are with the Division of General Internal Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore. Dr. Dixon is with the Department of Psychiatry, University of Maryland School of Medicine, Baltimore. Dr. Keating is with the Department of Health Care Policy, Harvard Medical School, Boston.

Notes

Send correspondence to Dr. Daumit at Johns Hopkins Medical Institutions, 2024 East Monument St., Suite 2-500, Baltimore, MD 21287 (e-mail: [email protected]).

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