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Abstract

Objective:

The objective of this review was to assess associations between Individual Placement and Support (IPS), employment, and personal and clinical recovery among persons with severe mental illness at 18-month follow-up.

Methods:

A systematic literature search identified randomized controlled trials (RCTs) comparing IPS with services as usual. Outcomes were self-esteem, empowerment, quality of life, symptoms of depression, negative or psychotic symptoms, anxiety, and level of functioning. A total of six RCTs reported data suitable for meta-analyses, and pooled original data from five studies were also analyzed.

Results:

Meta-analyses and analyses of pooled original data indicated that receipt of the IPS intervention alone did not improve any of the recovery outcomes. Participants who worked during the study period, whether or not they were IPS participants, experienced improved negative symptoms, compared with those who did not work (standardized mean difference [SMD]=−0.41, 95% confidence interval [CI]=−0.56, –0.26). For participants who worked, whether or not they were IPS participants, improvements were also found in level of functioning and quality of life (SMD=0.59, 95% CI=0.42, 0.77 and SMD=0.34, 95% CI=0.14, 0.54, respectively).

Conclusions:

Employment was associated with improvements in negative symptoms, level of functioning, and quality of life.

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Information & Authors

Information

Published In

Go to Psychiatric Services
Go to Psychiatric Services
Psychiatric Services
Pages: 1040 - 1047
PubMed: 33940948

History

Received: 1 February 2020
Revision received: 27 June 2020
Revision received: 28 September 2020
Revision received: 26 October 2020
Revision received: 10 November 2020
Accepted: 19 November 2020
Published online: 4 May 2021
Published in print: September 01, 2021

Keywords

  1. Recovery
  2. Rehabilitation/psychosocial

Authors

Details

Iben Gammelgaard Wallstroem, M.D., Ph.D. [email protected]
Research Unit of Mental Health and Department of Clinical Research, University of Southern Denmark, Odense, Denmark (Wallstroem); DEFACTUM, Central Denmark Region, and Department of Public Health, Aarhus University, Aarhus, Denmark (Pedersen); Copenhagen Research Center for Mental Health, Copenhagen (Christensen, Hellström, Bojesen, Eplov); Institute of Health and Medical Sciences, University of Copenhagen (Christensen); Research Unit of Mental Health, Aabenraa, Denmark, and Department of Regional Health Services, University of Southern Denmark, Odense, Denmark (Stenager); Population Health Research Institute, St. George’s University of London, London (White); Center for Psychiatric Rehabilitation, Boston University, Boston (Mueser); Department of Health Sciences, Lund University, Lund, Sweden (Bejerholm); University Medical Center Groningen, and University Center of Psychiatry, University of Groningen, Groningen, Netherlands (van Busschbach); Movisie and Trimbos Institute, Netherlands Institute of Mental Health and Addiction, Utrecht (Michon).
Pernille Pedersen, M.Sc., Ph.D.
Research Unit of Mental Health and Department of Clinical Research, University of Southern Denmark, Odense, Denmark (Wallstroem); DEFACTUM, Central Denmark Region, and Department of Public Health, Aarhus University, Aarhus, Denmark (Pedersen); Copenhagen Research Center for Mental Health, Copenhagen (Christensen, Hellström, Bojesen, Eplov); Institute of Health and Medical Sciences, University of Copenhagen (Christensen); Research Unit of Mental Health, Aabenraa, Denmark, and Department of Regional Health Services, University of Southern Denmark, Odense, Denmark (Stenager); Population Health Research Institute, St. George’s University of London, London (White); Center for Psychiatric Rehabilitation, Boston University, Boston (Mueser); Department of Health Sciences, Lund University, Lund, Sweden (Bejerholm); University Medical Center Groningen, and University Center of Psychiatry, University of Groningen, Groningen, Netherlands (van Busschbach); Movisie and Trimbos Institute, Netherlands Institute of Mental Health and Addiction, Utrecht (Michon).
Thomas Nordahl Christensen, M.Sc., Ph.D.
Research Unit of Mental Health and Department of Clinical Research, University of Southern Denmark, Odense, Denmark (Wallstroem); DEFACTUM, Central Denmark Region, and Department of Public Health, Aarhus University, Aarhus, Denmark (Pedersen); Copenhagen Research Center for Mental Health, Copenhagen (Christensen, Hellström, Bojesen, Eplov); Institute of Health and Medical Sciences, University of Copenhagen (Christensen); Research Unit of Mental Health, Aabenraa, Denmark, and Department of Regional Health Services, University of Southern Denmark, Odense, Denmark (Stenager); Population Health Research Institute, St. George’s University of London, London (White); Center for Psychiatric Rehabilitation, Boston University, Boston (Mueser); Department of Health Sciences, Lund University, Lund, Sweden (Bejerholm); University Medical Center Groningen, and University Center of Psychiatry, University of Groningen, Groningen, Netherlands (van Busschbach); Movisie and Trimbos Institute, Netherlands Institute of Mental Health and Addiction, Utrecht (Michon).
Lone Hellström, M.Sc., Ph.D.
Research Unit of Mental Health and Department of Clinical Research, University of Southern Denmark, Odense, Denmark (Wallstroem); DEFACTUM, Central Denmark Region, and Department of Public Health, Aarhus University, Aarhus, Denmark (Pedersen); Copenhagen Research Center for Mental Health, Copenhagen (Christensen, Hellström, Bojesen, Eplov); Institute of Health and Medical Sciences, University of Copenhagen (Christensen); Research Unit of Mental Health, Aabenraa, Denmark, and Department of Regional Health Services, University of Southern Denmark, Odense, Denmark (Stenager); Population Health Research Institute, St. George’s University of London, London (White); Center for Psychiatric Rehabilitation, Boston University, Boston (Mueser); Department of Health Sciences, Lund University, Lund, Sweden (Bejerholm); University Medical Center Groningen, and University Center of Psychiatry, University of Groningen, Groningen, Netherlands (van Busschbach); Movisie and Trimbos Institute, Netherlands Institute of Mental Health and Addiction, Utrecht (Michon).
Anders Bo Bojesen, M.Sc.
Research Unit of Mental Health and Department of Clinical Research, University of Southern Denmark, Odense, Denmark (Wallstroem); DEFACTUM, Central Denmark Region, and Department of Public Health, Aarhus University, Aarhus, Denmark (Pedersen); Copenhagen Research Center for Mental Health, Copenhagen (Christensen, Hellström, Bojesen, Eplov); Institute of Health and Medical Sciences, University of Copenhagen (Christensen); Research Unit of Mental Health, Aabenraa, Denmark, and Department of Regional Health Services, University of Southern Denmark, Odense, Denmark (Stenager); Population Health Research Institute, St. George’s University of London, London (White); Center for Psychiatric Rehabilitation, Boston University, Boston (Mueser); Department of Health Sciences, Lund University, Lund, Sweden (Bejerholm); University Medical Center Groningen, and University Center of Psychiatry, University of Groningen, Groningen, Netherlands (van Busschbach); Movisie and Trimbos Institute, Netherlands Institute of Mental Health and Addiction, Utrecht (Michon).
Elsebeth Stenager, M.D., Ph.D.
Research Unit of Mental Health and Department of Clinical Research, University of Southern Denmark, Odense, Denmark (Wallstroem); DEFACTUM, Central Denmark Region, and Department of Public Health, Aarhus University, Aarhus, Denmark (Pedersen); Copenhagen Research Center for Mental Health, Copenhagen (Christensen, Hellström, Bojesen, Eplov); Institute of Health and Medical Sciences, University of Copenhagen (Christensen); Research Unit of Mental Health, Aabenraa, Denmark, and Department of Regional Health Services, University of Southern Denmark, Odense, Denmark (Stenager); Population Health Research Institute, St. George’s University of London, London (White); Center for Psychiatric Rehabilitation, Boston University, Boston (Mueser); Department of Health Sciences, Lund University, Lund, Sweden (Bejerholm); University Medical Center Groningen, and University Center of Psychiatry, University of Groningen, Groningen, Netherlands (van Busschbach); Movisie and Trimbos Institute, Netherlands Institute of Mental Health and Addiction, Utrecht (Michon).
Sarah White, Ph.D.
Research Unit of Mental Health and Department of Clinical Research, University of Southern Denmark, Odense, Denmark (Wallstroem); DEFACTUM, Central Denmark Region, and Department of Public Health, Aarhus University, Aarhus, Denmark (Pedersen); Copenhagen Research Center for Mental Health, Copenhagen (Christensen, Hellström, Bojesen, Eplov); Institute of Health and Medical Sciences, University of Copenhagen (Christensen); Research Unit of Mental Health, Aabenraa, Denmark, and Department of Regional Health Services, University of Southern Denmark, Odense, Denmark (Stenager); Population Health Research Institute, St. George’s University of London, London (White); Center for Psychiatric Rehabilitation, Boston University, Boston (Mueser); Department of Health Sciences, Lund University, Lund, Sweden (Bejerholm); University Medical Center Groningen, and University Center of Psychiatry, University of Groningen, Groningen, Netherlands (van Busschbach); Movisie and Trimbos Institute, Netherlands Institute of Mental Health and Addiction, Utrecht (Michon).
Kim T. Mueser, Ph.D.
Research Unit of Mental Health and Department of Clinical Research, University of Southern Denmark, Odense, Denmark (Wallstroem); DEFACTUM, Central Denmark Region, and Department of Public Health, Aarhus University, Aarhus, Denmark (Pedersen); Copenhagen Research Center for Mental Health, Copenhagen (Christensen, Hellström, Bojesen, Eplov); Institute of Health and Medical Sciences, University of Copenhagen (Christensen); Research Unit of Mental Health, Aabenraa, Denmark, and Department of Regional Health Services, University of Southern Denmark, Odense, Denmark (Stenager); Population Health Research Institute, St. George’s University of London, London (White); Center for Psychiatric Rehabilitation, Boston University, Boston (Mueser); Department of Health Sciences, Lund University, Lund, Sweden (Bejerholm); University Medical Center Groningen, and University Center of Psychiatry, University of Groningen, Groningen, Netherlands (van Busschbach); Movisie and Trimbos Institute, Netherlands Institute of Mental Health and Addiction, Utrecht (Michon).
Ulrika Bejerholm, Ph.D.
Research Unit of Mental Health and Department of Clinical Research, University of Southern Denmark, Odense, Denmark (Wallstroem); DEFACTUM, Central Denmark Region, and Department of Public Health, Aarhus University, Aarhus, Denmark (Pedersen); Copenhagen Research Center for Mental Health, Copenhagen (Christensen, Hellström, Bojesen, Eplov); Institute of Health and Medical Sciences, University of Copenhagen (Christensen); Research Unit of Mental Health, Aabenraa, Denmark, and Department of Regional Health Services, University of Southern Denmark, Odense, Denmark (Stenager); Population Health Research Institute, St. George’s University of London, London (White); Center for Psychiatric Rehabilitation, Boston University, Boston (Mueser); Department of Health Sciences, Lund University, Lund, Sweden (Bejerholm); University Medical Center Groningen, and University Center of Psychiatry, University of Groningen, Groningen, Netherlands (van Busschbach); Movisie and Trimbos Institute, Netherlands Institute of Mental Health and Addiction, Utrecht (Michon).
Jooske Tanna van Busschbach, Ph.D.
Research Unit of Mental Health and Department of Clinical Research, University of Southern Denmark, Odense, Denmark (Wallstroem); DEFACTUM, Central Denmark Region, and Department of Public Health, Aarhus University, Aarhus, Denmark (Pedersen); Copenhagen Research Center for Mental Health, Copenhagen (Christensen, Hellström, Bojesen, Eplov); Institute of Health and Medical Sciences, University of Copenhagen (Christensen); Research Unit of Mental Health, Aabenraa, Denmark, and Department of Regional Health Services, University of Southern Denmark, Odense, Denmark (Stenager); Population Health Research Institute, St. George’s University of London, London (White); Center for Psychiatric Rehabilitation, Boston University, Boston (Mueser); Department of Health Sciences, Lund University, Lund, Sweden (Bejerholm); University Medical Center Groningen, and University Center of Psychiatry, University of Groningen, Groningen, Netherlands (van Busschbach); Movisie and Trimbos Institute, Netherlands Institute of Mental Health and Addiction, Utrecht (Michon).
Harry Michon, Ph.D.
Research Unit of Mental Health and Department of Clinical Research, University of Southern Denmark, Odense, Denmark (Wallstroem); DEFACTUM, Central Denmark Region, and Department of Public Health, Aarhus University, Aarhus, Denmark (Pedersen); Copenhagen Research Center for Mental Health, Copenhagen (Christensen, Hellström, Bojesen, Eplov); Institute of Health and Medical Sciences, University of Copenhagen (Christensen); Research Unit of Mental Health, Aabenraa, Denmark, and Department of Regional Health Services, University of Southern Denmark, Odense, Denmark (Stenager); Population Health Research Institute, St. George’s University of London, London (White); Center for Psychiatric Rehabilitation, Boston University, Boston (Mueser); Department of Health Sciences, Lund University, Lund, Sweden (Bejerholm); University Medical Center Groningen, and University Center of Psychiatry, University of Groningen, Groningen, Netherlands (van Busschbach); Movisie and Trimbos Institute, Netherlands Institute of Mental Health and Addiction, Utrecht (Michon).
Lene Falgaard Eplov, M.D., Ph.D.
Research Unit of Mental Health and Department of Clinical Research, University of Southern Denmark, Odense, Denmark (Wallstroem); DEFACTUM, Central Denmark Region, and Department of Public Health, Aarhus University, Aarhus, Denmark (Pedersen); Copenhagen Research Center for Mental Health, Copenhagen (Christensen, Hellström, Bojesen, Eplov); Institute of Health and Medical Sciences, University of Copenhagen (Christensen); Research Unit of Mental Health, Aabenraa, Denmark, and Department of Regional Health Services, University of Southern Denmark, Odense, Denmark (Stenager); Population Health Research Institute, St. George’s University of London, London (White); Center for Psychiatric Rehabilitation, Boston University, Boston (Mueser); Department of Health Sciences, Lund University, Lund, Sweden (Bejerholm); University Medical Center Groningen, and University Center of Psychiatry, University of Groningen, Groningen, Netherlands (van Busschbach); Movisie and Trimbos Institute, Netherlands Institute of Mental Health and Addiction, Utrecht (Michon).

Notes

Send correspondence to Dr. Wallstroem ([email protected]).

Competing Interests

The authors report no financial relationships with commercial interests.

Funding Information

Danish Agency for Labor Market and Recruitment
Danish nonprofit foundation TrygFonden
Obel Family Foundation: 26399
Psychiatric Research Foundation in Southern Denmark
University of Southern Denmark
The study was funded by the Danish Agency for Labor Market and Recruitment, the Danish nonprofit foundation TrygFonden, the Obel Family Foundation (grant 26399), the Psychiatric Research Foundation in Southern Denmark, and a faculty grant from the University of Southern Denmark.

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