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Published Online: 1 November 2002

Transcranial Magnetic Stimulation: A New Investigational and Treatment Tool in Psychiatry

Zafiris J. Daskalakis, M.D., Ph.D., F.R.C.P.C., Bruce K. Christensen, Ph.D., C.Psych., Paul B. Fitzgerald, M.B.B.S., M.P.M., F.R.A.N.Z.C.P., and Robert Chen, M.B.B.Chir., M.Sc., F.R.C.P.C.Authors Info & Affiliations
Publication: The Journal of Neuropsychiatry and Clinical Neurosciences
Volume 14, Number 4
https://doi.org/10.1176/jnp.14.4.406
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Abstract

Transcranial magnetic stimulation (TMS) is a new investigational technique used to explore various neural processes and treat a variety of neuropsychiatric illnesses. The most notable advantage of TMS is its ability to directly stimulate the cortex with little effect on intervening tissue. Single-pulse stimulation techniques can measure cortical inhibition, facilitation, connectivity, reactivity, and cortical plasticity, providing valuable insights into the cortical physiology. Repetitive TMS (rTMS) is currently being used to investigate cognitive processes and as a treatment tool in disorders such as depression and schizophrenia. Both TMS and rTMS are safe and well tolerated. The most serious side effect of high-frequency rTMS is seizures. TMS represents an exciting new frontier in neuroscience research, providing insights into the pathophysiology and treatment of various neuropsychiatric disorders.

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Information & Authors

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Published In

Go to The Journal of Neuropsychiatry and Clinical Neurosciences
Go to The Journal of Neuropsychiatry and Clinical Neurosciences
The Journal of Neuropsychiatry and Clinical Neurosciences
Volume 14 • Number 4 • November 2002
Pages: 406 - 415
PubMed: 12426408

History

Published online: 1 November 2002
Published in print: November 2002

Authors

Details

Zafiris J. Daskalakis, M.D., Ph.D., F.R.C.P.C.
Received March 19, 2001; revised July 11, 2001; accepted July 25, 2001. From the Centre for Addiction and Mental Health, University of Toronto, Ontario, Canada (z.j.d., b.k.c.); Dandenong Psychiatry Research Centre, Dandenong, Victoria, Australia (p.b.f.); and Division of Neurology, Toronto Western Hospital, University of Toronto, Ontario, Canada (r.c.). Address correspondence to Dr. Daskalakis, Schizophrenia and Continuing Care Program, Centre for Addiction and Mental Health, 7th Floor, Clarke Division, 250 College Street, Toronto, Ontario, Canada. E-mail: [email protected].
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Bruce K. Christensen, Ph.D., C.Psych.
Received March 19, 2001; revised July 11, 2001; accepted July 25, 2001. From the Centre for Addiction and Mental Health, University of Toronto, Ontario, Canada (z.j.d., b.k.c.); Dandenong Psychiatry Research Centre, Dandenong, Victoria, Australia (p.b.f.); and Division of Neurology, Toronto Western Hospital, University of Toronto, Ontario, Canada (r.c.). Address correspondence to Dr. Daskalakis, Schizophrenia and Continuing Care Program, Centre for Addiction and Mental Health, 7th Floor, Clarke Division, 250 College Street, Toronto, Ontario, Canada. E-mail: [email protected].
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Paul B. Fitzgerald, M.B.B.S., M.P.M., F.R.A.N.Z.C.P.
Received March 19, 2001; revised July 11, 2001; accepted July 25, 2001. From the Centre for Addiction and Mental Health, University of Toronto, Ontario, Canada (z.j.d., b.k.c.); Dandenong Psychiatry Research Centre, Dandenong, Victoria, Australia (p.b.f.); and Division of Neurology, Toronto Western Hospital, University of Toronto, Ontario, Canada (r.c.). Address correspondence to Dr. Daskalakis, Schizophrenia and Continuing Care Program, Centre for Addiction and Mental Health, 7th Floor, Clarke Division, 250 College Street, Toronto, Ontario, Canada. E-mail: [email protected].
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Robert Chen, M.B.B.Chir., M.Sc., F.R.C.P.C.
Received March 19, 2001; revised July 11, 2001; accepted July 25, 2001. From the Centre for Addiction and Mental Health, University of Toronto, Ontario, Canada (z.j.d., b.k.c.); Dandenong Psychiatry Research Centre, Dandenong, Victoria, Australia (p.b.f.); and Division of Neurology, Toronto Western Hospital, University of Toronto, Ontario, Canada (r.c.). Address correspondence to Dr. Daskalakis, Schizophrenia and Continuing Care Program, Centre for Addiction and Mental Health, 7th Floor, Clarke Division, 250 College Street, Toronto, Ontario, Canada. E-mail: [email protected].
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