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Published Online: 1 November 2003

Mesial Temporal Structures and Comorbid Anxiety in Refractory Partial Epilepsy

Parthasarathy Satishchandra, D.M., Ennapadam S. Krishnamoorthy, M.D., Ludger Tebartz van Elst, M.D., Louis Lemieux, Ph.D., Mathias Koepp, Ph.D., Richard J. Brown, Ph.D. , and Michael R. Trimble, M.D.Authors Info & Affiliations
Publication: The Journal of Neuropsychiatry and Clinical Neurosciences
Volume 15, Number 4
https://doi.org/10.1176/jnp.15.4.450
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Abstract

We used quantitative magnetic resonance imaging (MRI) to examine the mesial temporal structures in subjects with refractory partial epilepsy and comorbid anxiety and found preservation with a right-sided preponderance. The findings indicate a role for this brain region in the genesis of anxiety.

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Information & Authors

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Go to The Journal of Neuropsychiatry and Clinical Neurosciences
Go to The Journal of Neuropsychiatry and Clinical Neurosciences
The Journal of Neuropsychiatry and Clinical Neurosciences
Volume 15 • Number 4 • November 2003
Pages: 450 - 452
PubMed: 14627772

History

Published online: 1 November 2003
Published in print: November 2003

Authors

Affiliations

Parthasarathy Satishchandra, D.M.
Received May 23, 2002; revised September 13, 2002; accepted October 1, 2002. From the Raymond Way Neuropsychiatry Research Group & Epilepsy Research Group Institute of Neurology, London, United Kingdom. Address correspondence to Prof. M.R. Trimble, Queen Square, London WC1N 3BG, United Kingdom; [email protected] (E-mail).
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Ennapadam S. Krishnamoorthy, M.D.
Received May 23, 2002; revised September 13, 2002; accepted October 1, 2002. From the Raymond Way Neuropsychiatry Research Group & Epilepsy Research Group Institute of Neurology, London, United Kingdom. Address correspondence to Prof. M.R. Trimble, Queen Square, London WC1N 3BG, United Kingdom; [email protected] (E-mail).
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Ludger Tebartz van Elst, M.D.
Received May 23, 2002; revised September 13, 2002; accepted October 1, 2002. From the Raymond Way Neuropsychiatry Research Group & Epilepsy Research Group Institute of Neurology, London, United Kingdom. Address correspondence to Prof. M.R. Trimble, Queen Square, London WC1N 3BG, United Kingdom; [email protected] (E-mail).
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Louis Lemieux, Ph.D.
Received May 23, 2002; revised September 13, 2002; accepted October 1, 2002. From the Raymond Way Neuropsychiatry Research Group & Epilepsy Research Group Institute of Neurology, London, United Kingdom. Address correspondence to Prof. M.R. Trimble, Queen Square, London WC1N 3BG, United Kingdom; [email protected] (E-mail).
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Mathias Koepp, Ph.D.
Received May 23, 2002; revised September 13, 2002; accepted October 1, 2002. From the Raymond Way Neuropsychiatry Research Group & Epilepsy Research Group Institute of Neurology, London, United Kingdom. Address correspondence to Prof. M.R. Trimble, Queen Square, London WC1N 3BG, United Kingdom; [email protected] (E-mail).
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Richard J. Brown, Ph.D.
Received May 23, 2002; revised September 13, 2002; accepted October 1, 2002. From the Raymond Way Neuropsychiatry Research Group & Epilepsy Research Group Institute of Neurology, London, United Kingdom. Address correspondence to Prof. M.R. Trimble, Queen Square, London WC1N 3BG, United Kingdom; [email protected] (E-mail).
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Michael R. Trimble, M.D.
Received May 23, 2002; revised September 13, 2002; accepted October 1, 2002. From the Raymond Way Neuropsychiatry Research Group & Epilepsy Research Group Institute of Neurology, London, United Kingdom. Address correspondence to Prof. M.R. Trimble, Queen Square, London WC1N 3BG, United Kingdom; [email protected] (E-mail).
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