Drug Administration Schedules

ALBERTO DIMASCIO and RICHARD I. SHADERAuthors Info & Affiliations

Publication: American Journal of Psychiatry

Volume 126, Number 6

https://doi.org/10.1176/ajp.126.6.796

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Abstract

Common current practice is to prescribe psychotropic drugs so that a specified daily amount is administered in equally divided doses on a three to six times a day schedule. The authors contend that this procedure rests on no valid scientific basis. They cite a number of pharmacologic facts to bolster this conclusion and review the effects and effectiveness of various schedules of drug administration. They conclude that revisions can be made in the present methods of drug administration that result in great pragmatic benefit without loss of therapeutic effect.

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Information & Authors

Information

Published In

American Journal of Psychiatry

Volume 126 • Number 6 • December 1969

Pages: 796 - 801

PubMed: 5352210

History

Published in print: December 1969

Published online: 1 April 2006

Authors

Affiliations

ALBERTO DIMASCIO

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RICHARD I. SHADER

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Co-directors of the psychopharmacology research laboratory, Massachusetts Mental Health Center and director of psychopharmacology for the Commonwealth of Massachusetts Department of Mental Health, 591 Morton St., Boston, Mass. 02124, and associate professor of psychiatry, Tufts Medical School, Medford, Mass.

Co-directors of the psychopharmacology research laboratory, Massachusetts Mental Health Center and Associate clinical director, Massachusetts Mental Health Center, Boston, Mass., and assistant professor of psychiatry, Harvard Medical School, Cambridge, Mass.

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Drug Administration Schedules

Abstract

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