No access

Article

Published Online: February 1974

Lithium Prophylaxis in Recurrent Affective Illness

ROBERT F. PRIEN, C. JAMES KLETT, and EUGENE M. CAFFEY, JR.Authors Info & Affiliations

Publication: American Journal of Psychiatry

Volume 131, Number 2

https://doi.org/10.1176/ajp.131.2.198

Get Access

Abstract

The authors report on two recent two-year studies that attempted to determine the effectiveness of lithium carbonate in treating recurrent affective illness. In study I, 205 bipolar (manic-depressive) patients were randomly assigned to lithium or placebo; in study 2, 44 bipolar and 78 unipolar (depressive) patients were randomly assigned lithium, imipramine, or placebo. The results showed lithium to be effective in treating both manic and depressive episodes and imipramine to be effective in treating depressive episodes. The findings emphasize the importance of considering the patient's previous course of illness in selecting a program of maintenance treatment.

Get full access to this article

View all available purchase options and get full access to this article.

Get Access

Information & Authors

Information

Published In

American Journal of Psychiatry

Volume 131 • Number 2 • February 1974

Pages: 198 - 203

PubMed: 4587809

History

Published in print: February 1974

Published online: 1 April 2006

Authors

Details

ROBERT F. PRIEN

View all articles by this author

C. JAMES KLETT

View all articles by this author

EUGENE M. CAFFEY, JR.

View all articles by this author

Research Psychologist, at the Central Neuropsychiatric Research Laboratory, Veterans Administration Hospital, Perry Point, Md. 21902

Chief at the Central Neuropsychiatric Research Laboratory, Veterans Administration Hospital, Perry Point, Md. 21902

Deputy Director, Mental Health and Behavioral Sciences Service, Department of Medicine and Surgery, Veterans Administration, Washington, D.C.

Metrics & Citations

Metrics

Citations

Export Citations

If you have the appropriate software installed, you can download article citation data to the citation manager of your choice. Simply select your manager software from the list below and click Download.

For more information or tips please see 'Downloading to a citation manager' in the Help menu.

Format	RIS (ProCite, Reference Manager) EndNote BibTex Medlars RefWorks
Direct importt
Citation style
Style

Copy to clipboard
Tips for downloading citations

View Options

Get Access

Login options

Already a subscriber? Access your subscription through your login credentials or your institution for full access to this article.

Personal login Institutional Login Open Athens login

Purchase Options

Purchase this article to access the full text.

PPV Articles - American Journal of Psychiatry

Not a subscriber?

Subscribe Now / Learn More

PsychiatryOnline subscription options offer access to the DSM-5-TR^® library, books, journals, CME, and patient resources. This all-in-one virtual library provides psychiatrists and mental health professionals with key resources for diagnosis, treatment, research, and professional development.

Need more help? PsychiatryOnline Customer Service may be reached by emailing [email protected] or by calling 800-368-5777 (in the U.S.) or 703-907-7322 (outside the U.S.).

Lithium Prophylaxis in Recurrent Affective Illness

Abstract

Get full access to this article