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First-Episode Psychosis and Prodrome Workup | Therapeutic Interventions | Prevention of Adverse Outcomes | Conclusion | References

Excerpt

Early stages of schizophrenia have not always been conceptualized as being on the continuum with chronic stages of the disease. In fact, historically, treatment was withheld until symptom presentation had solidified into systematically defined schizophrenia. During the 1980s, researchers and clinicians began to recognize that delay in treatment, including the initiation of antipsychotic medications, could lead to poor social, cognitive, and functional outcomes (Johnstone et al. 1986). This revelation prompted further research into the detrimental impact of longer duration of untreated psychosis—that is, the time from onset of schizophrenia symptoms to initiation of medication treatment. These studies led to substantial examination of the assessment and management of schizophrenia in young people and the development of revised clinical programs worldwide (Perkins et al. 2005).

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