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Alzheimer’s disease (AD) is a slowly progressive neurocognitive disorder with a preclinical phase in which the individual may be asymptomatic for many years. This preclinical phase is followed by a period, generally termed mild cognitive impairment (MCI), of impaired cognition and possible neuropsychiatric symptoms without functional deficit. Eventually, individuals with AD develop a dementia or neurocognitive syndrome with cognitive deficits, functional decline, and neuropsychiatric symptoms. The DSM-5 criteria for major or mild neurocognitive disorder due to AD are listed in Box 64- (American Psychiatric Association 2013).
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