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Frontotemporal neurocognitive disorder (FTNCD) represents a spectrum of neurodegenerative diseases that compromise function of frontal brain networks, resulting in cognitive and behavioral deficits (see Box 65-). More often referred to as frontotemporal dementia in the medical literature, FTNCD is a common cause of dementia among patients ages 45–65 years and comprises two sometimes overlapping clinical syndromes: behavioral-variant frontotemporal neurocognitive disorder (Bv-FTNCD) and language-variant frontotemporal neurocognitive disorder (Lv-FTNCD) (Table 3-). The latter syndrome includes two subtypes: progressive nonfluent aphasia (PNFA) and semantic dementia.
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