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Combat injury has a profound effect on military service members, impacting their psychological and physical functioning as well as their interpersonal lives. During the acute phase of medical care, treatment is often complicated by delirium, pain, and sleep deprivation as well as iatrogenic issues such as drug interactions and nosocomial infections. Further complications may arise as a result of traumatic brain injuries (TBIs) and can present unique challenges for clinicians and patients. In this chapter we review the physical and psychological sequelae of severe combat injury and the unique challenges of working with patients who have been injured in a combat theater, as well as the important psychotherapeutic and psychopharmacological approaches that serve to support recovery in the short term and over time.
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