LGBT youths have unique mental health needs of which the general clinician should be aware. Although most are generally healthy, they frequently have distinctive developmental experiences and stressors that place them at elevated risk. A growing evidence base, including detailed reports and practice parameters published by organizations such as the Institute of Medicine and the American Academy of Child and Adolescent Psychiatry, is available to guide clinicians in providing competent clinical care.
Historically, the stigma associated with being gay, lesbian, or bisexual was exacerbated by the psychiatric diagnosis of homosexuality. That diagnosis was removed from the
DSM-II in 1973 (
1,
2) and from the
ICD-10 in 1992 (
3). The diagnostic status of transgender and gender diverse individuals is a matter of ongoing discussion and revision (
4).
A number of medical organizations have comprehensively reviewed the health status and needs of LGBT youths. These reviews, summarized below, include information about physical and mental health disparities among LGBT youths and discuss the etiology, treatment, prevention, and research needs for many of these issues. Transgender youths have been particularly understudied. Key findings are summarized for lesbian, gay, and bisexual or for transgender youths accordingly.
Mental Health Needs of LGBT Youths
Unique Developmental Experiences of LGBT Youths
LGBT youths have the same developmental needs as the general population. In addition, clinicians providing care to LGBT youths should consider this population’s unique needs in four important developmental domains influencing health and mental health: sexual orientation, sexual identity or sexual orientation identity, gender expression, and gender identity.
Sexual orientation refers to the gender(s) of those to whom an individual is sexually or romantically attracted: homosexual (same sex), heterosexual (other sex), and bisexual (both male and female). An individual’s sexual identity or sexual orientation identity is referred to with the terms lesbian, gay, and bisexual. Gender expression refers to the degree of gender typicality of a child or youth’s play preferences (including toys and inclination for rough-and-tumble play), use of styles, mannerisms, and other gender-typed behavior. Gender identity refers to the gender with which the individual identifies, and may or may not be congruent with gender expression. For example, an adolescent may have a private female gender identity and a public male gender expression. Some terms that can be used to describe gender identity include girl, boy, nonbinary, agender, and genderqueer, although there are many others. Clinicians working with LGB and gender dysphoric youths can learn to distinguish the four developmental domains. Stressors related to development in one or more domains can result in adverse experiences for the patient.
Gender dysphoria, a persistent and severe emotional distress related to one’s gender identity and a desire to be an alternative gender different from one’s assigned gender, differs from gender nonconformity. Gender nonconformity refers to the behavioral expression of gender-typed traits in a given sociocultural context; it is distinct from the identity component of gender dysphoria, which refers to a psychological experience of one’s gender rather than to gender-related behavior. These can be congruent but are not necessarily so.
Individuals exposed to negative reactions about their gender or sexual identity from peers, family, or society are at increased risk for psychological distress. The rates at which LGBT youths experience depression, anxiety, and substance abuse are increased compared with the general population and include a two-to-fourfold increased risk for suicidality (ideation and behavior) (
11). Exposure to interpersonal stigma, such as family rejection and harassment from peers, has been associated with greater risk for suicidality. Fear of rejection or risk of physical or emotional harm because of divergence in sexual or gender development can often lead pediatric patients to hide their feelings, such as experiencing same-sex romantic attraction, variation in gender expression, and gender dysphoria. Hiding one’s identity, and the dilemma over whether to come out (reveal one’s identity) to peers and family, are experiences unique to the emotional development of LGBT youths. In addition, transgender youths sometimes have unique medical and mental health needs related to the distress they may experience because of discordance between their gender identity and their assigned birth gender. Mental health clinicians and pediatricians familiar with these concepts are best able to appropriately discuss sexual orientation, gender expression, and gender identity with their patients (
6).
Minority Stress and Stigma
The minority stress hypothesis (
12) provides a conceptual framework for understanding the increased rates of physical and mental health disparities among the LGBT population. This hypothesis posits that exposure to anti-LGBT stigma causes the disparities found among LGBT youths. Examples of stigma include family nonacceptance; peer bullying; employment or housing discrimination; criminalization of same-sex or transgender behavior; reality-based identity concealment and rejection anticipation; and exposure to discriminatory laws, policies and societal norms.
The bulk of sexual and gender minority stress research, however, has been conducted with LGBT adults. Goldbach and Gibbs used qualitative methods to address the applicability of minority stress theory to LGBT adolescents, finding that although the model applies, further attention in adolescents should be devoted to group- and individual-level coping resources, social and family context, and sexual identity development (
13). They further note that, whereas the original model emphasizes negative expectations as an internal factor, assessing expectations of actual acceptance is of unique developmental importance among LGBT adolescents. Although it may be challenging to reduce sources of social stress, the presence of coping resources may be another clinically modifiable factor. The proposed emphasis on social and family context for gender and sexual minority adolescents is concordant with data demonstrating the importance of family acceptance and school safety as protective factors (
14). Finally, identity formation is a central developmental task of adolescence, such that the development and integration of sexual and gender identity pose an additional developmental challenge that may be influenced by exposure to stigma.
The multiple levels at which minority stress operates—individual, interpersonal, and structural (i.e., laws, policies, and norms)—underscore the role of mental health professionals at each of these levels (
15,
16). Individual-level interventions include using various psychotherapeutic modalities aimed at helping LGBT youths cope with stress. One randomized controlled trial assessed the efficacy of a modified cognitive-behavioral therapy intervention for gay and bisexual young men, showing positive outcomes on depression, alcohol use, and HIV risk behavior (
16). Interpersonal-level interventions include family-focused interventions aimed at increasing family acceptance and support; identification of key social and family contexts through which LGBT youths experience minority stress; school-based interventions geared toward increasing school acceptance and safety; and collaborative and consultative work with other mental and physical health practitioners to promote access to LGBT-affirmative health care. Structural-level approaches include advocacy and policy development at state, local, and institutional levels. All three levels are critical targets for improving health outcomes for LGBT youths.
Treatment of Mental Health Issues
The AACAP’s practice parameter on the assessment and treatment of children and adolescents with depressive disorders (
17) is one of several publications available to guide mental health clinicians in providing treatment to all youths. This document advises routine screening for depression in all psychiatric assessments of children and adolescents. Early identification and effective treatment of unipolar and bipolar depression, substance- or medication-induced depression, depressive disorders caused by medical conditions, dysthymia, and adjustment disorders leads to reduction in illness severity and lower rates of suicide, substance abuse, and persistence of depression into adulthood. These principles, carried out with appropriate clinical and cultural competence, are applicable to LGBT youths and are further described in the AACAP practice parameter.
Mental health professionals can help LGBT youths improve social support, coping methods, and problem-solving skills. Anti-LGBT stigma that has contributed to a depressive episode may persist after the depressive episode has been resolved, and continued psychotherapy may be needed to maintain remission by supporting ongoing coping with this stigma or with related psychosocial, familial, and interpersonal stressors and conflicts. Continued parent-child conflict has been associated with prolonged episodes of depression and increased rates of relapse. Irritability and conflictual relationships—common features of depression among youths—may strain interpersonal relationships. As a result, potentially supportive peers and family may withdraw from the adolescent, leading to increased feelings of isolation for the adolescent. It is important to assess the youth’s social network at the beginning of treatment. The strength of this social network may be especially strained, and complicated by lack of acceptance from peers and family, for adolescents who are transgender, gender diverse, or members of a sexual minority. Therefore, clinicians may need to consider specific stressors related to sexual orientation, gender expression, and/or gender identity, in addition to other psychosocial and contextual issues, for youths who do not respond to standard treatments for depression.
Standard, developmentally appropriate treatment for mild-to-moderate depressive illness may include supportive psychotherapy or structured treatments, such as interpersonal psychotherapy, cognitive-behavioral therapy, or psychodynamic psychotherapy. In addition, school and family or caregiver interventions may be key components of treatment for children and adolescents (
17).
Clinicians should be mindful regarding issues of confidentiality and disclosure when engaging the LGBT’s patient’s support system. Principle 2 of the AACAP’s practice parameter (
7) says, “the need for confidentiality in the clinical alliance is a special consideration in the assessment of sexual and gender minority youth.” Clinicians must consider the patient’s safety; acceptance or rejection by family, community, and school; and support available or absent when working with a patient regarding disclosure of a transgender, gender diverse, and/or LGBT identity (i.e., when and to whom a patient is considering coming out).
Clinicians should be prepared to address the complexity of a patient’s decision to come out. Doing so may be relatively simple if the child has a supportive family and school system. However, the issue is more complicated when disclosure of gender or sexual minority status may cause harm to the child or adolescent. The coming out process varies from patient to patient. Clinicians should consider how unique clinical factors, including the psychosocial context, influence whether, how, and when coming out is appropriate for a given youth. In planning treatment, practitioners should consider opportunities to strengthen the relationship between the child and family or caregiver, guide caregivers in providing support, help to manage family crises, and decrease interpersonal and familial conflicts (
7).
LGBT youths also face unique challenges when seeking substance use treatment, especially when there is family involvement or a recommendation for residential treatment. Clinicians should consider gender and sexual identity development when formulating the treatment plan, keeping in mind that the treatment setting works best when it is welcoming, nonjudgmental, and open to affirming the youth’s gender and sexual identity (
18).
Support for Families of Transgender Youths
In addition to stigma, transgender and gender diverse youths and their families may face additional stress related to decision-making regarding transgender-specific social and medical interventions to affirm gender identity. A
social transition, which involves no medical or surgical intervention, can be accomplished in many ways and to multiple degrees. This transition involves, for example, choosing a hairstyle and clothing that reflect one’s gender identity or using a name and pronouns congruent with one’s gender identity. Social transition can occur across all environments, or may be limited to specific settings, such as in the home, at specific supportive events, or on vacation. Although there is little empirical evidence on the risks and benefits of early social transitioning among gender dysphoric youths, preliminary information from Dutch cohort studies in specialty clinics has identified some factors associated with a higher likelihood that prepubertal gender dysphoria will continue into adolescence. These factors include a greater intensity of dysphoria and meeting criteria for a formal diagnosis; a cognitive or affective cross-gender identification (that is, saying “I am” or “I feel like” rather than “I wish I were the other sex”); having a younger age of presentation; having a male birth gender assignment; and having gone through an early social role transition, especially for those assigned male at birth (
19,
20).
Several clinical cohorts have found that the developmental trajectory of gender dysphoria among children is more variable than that among adults, with a majority not reporting gender dysphoria persisting into adolescence or young adulthood (
19–
23). In a number of clinical cohorts, gender dysphoria manifesting in adolescence and adulthood has tended to be stable over time. In contrast, in a number of specialty clinic cohorts, a majority of gender dysphoric prepubertal children have no longer reported gender dysphoria in adolescence or young adulthood. Instead, a majority have reported a nonheterosexual orientation. This finding has been questioned because of a number of possible confounders, including selection bias for patients more likely to disavow transgender identity over time, identity concealment because of stigma in adolescence or adulthood, and/or overly broad initial inclusion criteria (
24). Further research including population-based samples and long-term follow-up is needed to rule out such confounders or other sources of misclassification.
Mental health professionals can consider helping children and families evaluate their options, weigh risks and benefits, and tolerate uncertainty.
Gender transition is a highly complex process, and clinicians who have experience with assisting patients in transition should be consulted. They can provide guidance on how to support families in making and executing decisions about the timing and nature of steps toward social transition and can help families affirm and support a gender dysphoric child, even if social gender transition is not undertaken. Mental health professionals can help families navigate and advocate for their child in the school and community (e.g., access to bathrooms at school), and, as puberty approaches, help pave the way for decision making about hormonal interventions. This decision making may include considering reversible suppression of puberty with gonadotropin-releasing hormone analogs, and possibly at a later stage, use of irreversible cross-gender hormones, including estrogens and testosterone (
25).
Clinicians can discuss the risks and benefits of social and medical transition with patients in a developmentally appropriate manner, especially when social transition is being considered by prepubertal children. The clinician can consider the risk of later distress due to posttransition regret, if cross-gender identity fades postpubertally, and can weigh this risk against the potential benefit of a prepubertal gender transition that might improve the psychosocial functioning of children whose transgender identity is affirmed by others. Clinicians can consider helping children to explore their gender, supporting the family when there is uncertainty in whether the gender dysphoria will remain stable over time, and encouraging caregivers to provide children with support and acceptance as their gender identity becomes clear. The Fenway Guide also addresses limitations on current clinical knowledge and the need for more research in this population in order to develop and update clinical practice guidelines (
26).
Collaboration With Pediatricians
Collaboration between mental health clinicians and pediatricians is key to providing competent psychiatric care to LGBT youths, particularly because the majority of LGBT youths are seen by pediatricians and not by the limited supply of mental health professionals. This care may range from medical treatment of gender dysphoria to ensuring a patient has access to a medical home where patient-centered, team-based comprehensive and continuous medical care is provided by clinicians and basic primary care needs are met. Social stressors, such as stigma, parental and community rejection, and social isolation place LGBT youths at risk of experiencing health inequities compared with their non-LGBT peers. As a result of both increased rates of psychiatric illness influencing health risk behaviors and epidemic patterns, LGBT youths may be at increased risk of engaging in behaviors that expose them to sexually transmitted infections, including HIV; sexual assault or abuse; and teen pregnancy (
27). For example, men who have sex with men account for approximately 4% of the male U.S. population, yet they make up 78% of new HIV infections among men and 68% of total new HIV infections (
27). Reported sexual attraction does not always align with sexual behavior among youths, and a majority of young women who have sex with women report previous male partners. Discussions about sexual and reproductive health and future family planning intentions may help clinicians to understand how LGBT youths see themselves in the future and how they conceptualize family. It is important to avoid making assumptions about pregnancy risk or fertility intentions of LGBT youths (
27).
An additional issue that brings psychiatric clinicians to work closely with pediatricians is the treatment of eating disordered behavior. Up to 25% of high-school-age girls and 11% of high-school-age boys report engaging in eating disordered behavior, including daily vomiting to control weight (
28). In general, eating disordered behaviors peak in adolescence, which is also a key period in sexual identity development. LGBT youths with eating disorders may be affected in unique ways. Issues related to LGBT identity and family acceptance may arise in treatment of eating disorders, because most treatments are family based. In addition, gay and bisexual boys have been found to have increased body image and weight concerns, viewing themselves as overweight when they are in a healthy weight rage, and lesbians have been found to view themselves as in the normal range when they are in fact in the obese or overweight range (
14). Body image concerns, distortions in body image, or general body dissatisfaction are prevalent, albeit not ubiquitous, concerns of gender dysphoric youths (
28). The intersection between transgender identity and eating disorders remains understudied. Appropriate care for gender dysphoric youths with concomitant eating disorders should include affirmation of and appropriate medical support for the youths’ gender identity (
28).