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Case Report
Published Online: 11 July 2024

Dementia With Lewy Bodies Phenocopy in a Case of RT-QuIC–Negative Creutzfeldt-Jakob Disease: Implications of Functional Anatomy

Molly K. Wiggins, M.D. [email protected], Emily P. Pharr, M.D., Jennifer L. Wood, M.S.P.A.S., P.A.-C., Suzanne Craft, Ph.D., William T. Harrison, M.D., and James R. Bateman, M.D., M.P.H.Authors Info & Affiliations
Publication: The Journal of Neuropsychiatry and Clinical Neurosciences
Preprint
https://doi.org/10.1176/appi.neuropsych.20230205
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Information & Authors

Information

Published In

Go to The Journal of Neuropsychiatry and Clinical Neurosciences
Go to The Journal of Neuropsychiatry and Clinical Neurosciences
The Journal of Neuropsychiatry and Clinical Neurosciences
Preprint

History

Received: 16 November 2023
Revision received: 29 February 2024
Revision received: 25 March 2024
Accepted: 2 April 2024
Published online: 11 July 2024

Keywords

  1. Alzheimer’s Disease
  2. Dementia With Lewy Bodies
  3. Diffusion-Weighted MRI
  4. Geriatric Neuropsychiatry
  5. Posterior Cortical Atrophy
  6. Prion Disease

Authors

Details

Molly K. Wiggins, M.D. [email protected]
Department of Neurology (Wiggins, Pharr, Wood, Bateman), Department of Internal Medicine, Division of Gerontology and Geriatric Medicine (Craft, Bateman), Alzheimer’s Disease Research Center (Craft, Harrison), Department of Pathology (Harrison, Bateman), and Department of Psychiatry and Behavioral Medicine (Bateman), Wake Forest School of Medicine, Winston-Salem, N.C.; Mental Illness Research, Education, and Clinical Center, Salisbury Veterans Affairs Medical Center, Salisbury, N.C. (Bateman).
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Emily P. Pharr, M.D.
Department of Neurology (Wiggins, Pharr, Wood, Bateman), Department of Internal Medicine, Division of Gerontology and Geriatric Medicine (Craft, Bateman), Alzheimer’s Disease Research Center (Craft, Harrison), Department of Pathology (Harrison, Bateman), and Department of Psychiatry and Behavioral Medicine (Bateman), Wake Forest School of Medicine, Winston-Salem, N.C.; Mental Illness Research, Education, and Clinical Center, Salisbury Veterans Affairs Medical Center, Salisbury, N.C. (Bateman).
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Jennifer L. Wood, M.S.P.A.S., P.A.-C.
Department of Neurology (Wiggins, Pharr, Wood, Bateman), Department of Internal Medicine, Division of Gerontology and Geriatric Medicine (Craft, Bateman), Alzheimer’s Disease Research Center (Craft, Harrison), Department of Pathology (Harrison, Bateman), and Department of Psychiatry and Behavioral Medicine (Bateman), Wake Forest School of Medicine, Winston-Salem, N.C.; Mental Illness Research, Education, and Clinical Center, Salisbury Veterans Affairs Medical Center, Salisbury, N.C. (Bateman).
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Suzanne Craft, Ph.D.
Department of Neurology (Wiggins, Pharr, Wood, Bateman), Department of Internal Medicine, Division of Gerontology and Geriatric Medicine (Craft, Bateman), Alzheimer’s Disease Research Center (Craft, Harrison), Department of Pathology (Harrison, Bateman), and Department of Psychiatry and Behavioral Medicine (Bateman), Wake Forest School of Medicine, Winston-Salem, N.C.; Mental Illness Research, Education, and Clinical Center, Salisbury Veterans Affairs Medical Center, Salisbury, N.C. (Bateman).
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William T. Harrison, M.D.
Department of Neurology (Wiggins, Pharr, Wood, Bateman), Department of Internal Medicine, Division of Gerontology and Geriatric Medicine (Craft, Bateman), Alzheimer’s Disease Research Center (Craft, Harrison), Department of Pathology (Harrison, Bateman), and Department of Psychiatry and Behavioral Medicine (Bateman), Wake Forest School of Medicine, Winston-Salem, N.C.; Mental Illness Research, Education, and Clinical Center, Salisbury Veterans Affairs Medical Center, Salisbury, N.C. (Bateman).
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James R. Bateman, M.D., M.P.H.
Department of Neurology (Wiggins, Pharr, Wood, Bateman), Department of Internal Medicine, Division of Gerontology and Geriatric Medicine (Craft, Bateman), Alzheimer’s Disease Research Center (Craft, Harrison), Department of Pathology (Harrison, Bateman), and Department of Psychiatry and Behavioral Medicine (Bateman), Wake Forest School of Medicine, Winston-Salem, N.C.; Mental Illness Research, Education, and Clinical Center, Salisbury Veterans Affairs Medical Center, Salisbury, N.C. (Bateman).
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Notes

Send correspondence to Dr. Wiggins ([email protected]).

Competing Interests

Dr. Craft has served on the scientific advisory boards for the Neurodegeneration Consortium and T3D Therapeutics. Dr. Bateman has received research funding from the Alzheimer’s Association, Dementia Alliance of North Carolina, and NIH; he has received honoraria from the North Carolina Area Health Education Center and Novo Nordisk for participation in educational activities. The other authors report no financial relationships with commercial interests.

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