A Collaborative Care Approach to Depression Treatment for Asian Americans

Funded by the State of Washington and King County and administered by the Community Health Plan of Washington State in collaboration with Public Health of Seattle and King County, MHIP provides integrated mental health services for safety net populations through a network of CHCs (integratedcare-nw.org). The CHCs use a collaborative team approach that includes a primary care provider, care coordinator based in the primary care clinic, and consulting psychiatrist. Care coordinators and consulting psychiatrists use a Web-based care management tracking system (CMTS) adapted from an earlier research trial (6) to monitor the care and outcomes of patients. Validated questionnaires, such as the nine-item Patient Health Questionnaire (PHQ-9) (10), are used to track clinical outcomes. For non–English-speaking patients, either the care coordinator or a clinic translator works with the patient to complete the PHQ-9 ratings. Intake and follow-up contacts are documented in the tracking system in real time, which allows for a prospective examination of treatment processes and clinical outcomes. Treatment is standardized across participating clinics through shared training materials and processes and documentation of initial and follow-up care in structured encounter forms presented by CMTS. All clinics are evaluated with a shared set of quality aims that have been associated with improved treatment outcomes (9).

We included all eligible adult Asian patients and a comparison sample of white patients who participated in MHIP between 2008 and 2010 and had significant depression (an intake PHQ-9 score of ≥10) (10,11). The final sample comprised 129 Asian patients served in the culturally sensitive clinic, 72 Asian patients served in 12 general clinics that serve the general population, and 144 age- and gender-matched white patients served in the same general clinics. Our analyses were conducted with deidentified data extracted from the CMTS in early 2011 to ensure that each patient had at least 16 weeks of potential observation time after MHIP enrollment. The data were collected for quality improvement activities that were not considered research; thus individual patient consent was not required by the University of Washington’s Institutional Review Board.

Treatment processes examined included psychiatric case reviews, receipt of psychotropic medications, and number of follow-up contacts with a care coordinator during a 16-week period after program enrollment. The PHQ-9 (10,11) was used to measure depression severity at baseline and follow-up assessments. Depression improvement at 16 weeks—a sufficient amount of time to support at least one complete treatment trial (10)—was examined with a last-observation-carried-forward approach. Depression improvement was defined as achieving a PHQ-9 score <10 or a ≥50% reduction from baseline at 16-week follow-up assessment.

Other sample characteristics, based on self-report at intake, included age, gender, problems with social support, and unstable housing. A probable anxiety disorder was defined as a score ≥10 on the seven-item Generalized Anxiety Disorder scale (10) or a previously documented anxiety disorder diagnosis. Data on thoughts of suicide or death were obtained through self-report or an endorsement at baseline of a score ≥1 on item 9 of the PHQ-9 (“thoughts that you would be better off dead, or of hurting yourself in some way”).

Descriptive analyses included chi square tests and t tests for comparison of baseline characteristics. To examine whether there were differences in treatment process and depression outcomes between Asians served in the culturally sensitive clinic and Asian patients served in the general clinics and between Asian patients and white patients served in general clinics at follow-up, adjusted means of outcome measures were estimated and tested (any follow-up contact in four weeks of treatment, number of follow-up contacts in 16 weeks, and depression improvement at 16 weeks). Estimates were adjusted for baseline age, gender, PHQ-9 score, anxiety, suicidal thoughts, problems with social support and housing, and length of treatment. We applied mixed-effects logistic modeling for binary outcomes and mixed-effects Poisson modeling for count of follow-up contacts, taking into account nesting of patients within participating CHCs. Analysis was completed with Stata, version 11.

There were no significant differences in baseline PHQ-9 depression scores among the three populations studied (Table 1). Asians served at the culturally sensitive clinic were significantly older than Asians in the general clinics and somewhat less likely to have comorbid anxiety. There were no significant differences between groups with regard to gender, suicidal thoughts, problems with social support, or unstable housing.

After adjustment for differences in baseline characteristics, all three groups had similar treatment processes and depression outcomes (Table 2). Depression improvement was achieved at 16 weeks for an average of 28% of the patients evaluated in this study. The rate of improvement was slightly higher for Asians in the culturally sensitive clinic (35%) than for Asians served in general clinics (24%) or for age- and gender-matched whites (22%), but these differences were not statistically significant. Asians served in the culturally sensitive clinic were significantly less likely to receive psychotropic medications than Asians served in general clinics (51% versus 67%; p≤.05).

Our study demonstrates that collaborative care in CHCs was similarly effective for Asian Americans and whites. This finding is consistent with other studies showing that persons in racial-ethnic minority groups benefit from collaborative care in community health clinics (7,8,12). The overall response rate observed at 16 weeks is slightly higher than published depression response rates from patients receiving treatment at public-sector clinics (13) and slightly lower than improvement rates reported from private psychiatry practices (14). A longer observation time in future studies may result in higher response rates, according to a recent study that used the same data source and reported that depression improvement did not occur until an average of 24 weeks (9).

Study limitations include the fact that we were not able to characterize the diversity of Asian-American groups represented in this sample, which makes generalization to Asian populations imprudent. The fact that the population of patients served in the culturally sensitive clinic included approximately 40% Chinese and 25% Vietnamese patients, who spoke mainly Cantonese (30%), Vietnamese (25%), and English (22%), would suggest that a large percentage of patients included in this study were Chinese and Vietnamese and that the collaborative care program was able to engage non–English-speaking clinic patients. Future research in which more detailed racial-ethnic data are collected would be useful.

Despite the limitations of this study, several important findings emerged in regard to providing mental health care for Asian populations. For example, Asians in the culturally sensitive clinic were less likely to receive psychotropic medications than those in general clinics but had clinical outcomes that were at least as good as those served in other clinics. Asian Americans may be less comfortable than white Americans with the notion of taking a psychotropic medication (15), and providers in the culturally sensitive clinic may be sensitive to this preference. Alternatively, Asian Americans served in general clinics may have been somewhat more acculturated than Asians served in the culturally sensitive clinic and thus more accepting of medications.

Although all three groups had similar reductions in depression, the larger group of Asian patients received treatment at the culturally sensitive clinic (129 versus 72), indicating that the specialty clinic was able to engage almost twice as many Asian Americans as engaged by the equivalent of nearly ten general community health clinics in the same geographic area. Our findings are consistent with a recent study (12) that showed that collaborative care was effective in engaging and treating Chinese Americans. The culturally sensitive clinic has a strong commitment to community outreach programs to engage Asian and other immigrant populations in primary care, and it provided care that was at least as effective as that provided in other clinics. Future research and quality improvement efforts might explore prescribing practices in the culturally sensitive clinic and encourage use of psychotropic medications for patients who are not improving with psychosocial interventions alone. On the other hand, lessons from engagement and treatment approaches at the culturally sensitive clinic might provide important strategies for the engagement and care of Asian Americans in other community health clinics.

Collaborative care for depression in community health clinics was equally effective for Asian Americans as for age- and gender-matched whites. Culturally sensitive clinics that treat Asian Americans may be particularly well positioned to engage and care for this population.

Dr. Unützer was supported by grant NIMH2 T32 MH 73553-6 from the National Institute of Mental Health. The authors thank Community Health Plan of Washington (CHPW) and Public Health of Seattle and King County for sponsorship and funding of the MHIP and for data on quality of care and clinical outcomes. The authors also thank program leadership from CHPW, clinicians and leadership in the participating CHCs, consulting psychiatrists and trainers, and program support staff at the AIMS Center (Advancing Integrated Mental Health Solutions) at the University of Washington for their ongoing contributions to MHIP.

Dr. Ratzliff is a consulting psychiatrist on a contract from CHPW to the University of Washington that supports training, technical assistance, and quality improvement for the MHIP. The other authors report no competing interests.