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Research Article
Published Online: August 1996

Sertraline in the treatment of severe aggressiveness in Huntington's disease

Publication: The Journal of Neuropsychiatry and Clinical Neurosciences

Abstract

Sertraline, a selective serotonin reuptake inhibitor, was used to treat two consecutive cases of genetically confirmed Huntington's disease in which severe irritability and aggressiveness required inpatient admission. The complete cessation of aggressive behavior in both cases has been maintained on follow-up. This report adds to the literature implicating serotonergic mechanisms in irritability and aggressiveness in both neuropsychiatric and idiopathic psychiatric disorders.

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Go to The Journal of Neuropsychiatry and Clinical Neurosciences
Go to The Journal of Neuropsychiatry and Clinical Neurosciences
The Journal of Neuropsychiatry and Clinical Neurosciences
Pages: 338 - 340
PubMed: 8854307

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Published in print: August 1996
Published online: 1 April 2006

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