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The Journal of Neuropsychiatry and Clinical Neurosciences

  • Volume 8
  • Number 3
  • August 1996

Publication date: 01 August 1996

Pages249–261

The authors review neurophysiological, neurobehavioral, and neuropsychological investigations of the orbital frontal cortex (OFC) in human and non-human primates. The article critically examines the role of the OFC in 1) recognition of reinforcers; 2) ...

https://doi.org/10.1176/jnp.8.3.249

Publication date: 01 August 1996

Pages262–269

Whether or not drug use can cause a chronic psychotic disorder that is clinically similar to schizophrenia and related disorders is an important question. In this review, the authors attempt to determine whether there is enough evidence in the literature ...

https://doi.org/10.1176/jnp.8.3.262

Publication date: 01 August 1996

Pages270–275

Twenty-one depressed patients with probable Alzheimer's disease (AD) were randomized to receive a 6-week treatment with clomipramine or placebo in a study with a double-blind crossover design. Main outcome measures were Hamilton Depression, Mini-Mental ...

https://doi.org/10.1176/jnp.8.3.270

Publication date: 01 August 1996

Pages276–280

The records of 49 patients with Parkinson's disease and psychosis who were treated with clozapine for up to 18 months were reviewed. Average starting dose of clozapine was 16 mg. Average maximum dose was 39 mg. The psychotic symptoms improved in 76% of ...

https://doi.org/10.1176/jnp.8.3.276

Publication date: 01 August 1996

Pages281–286

The authors evaluated 14 middle-aged and elderly patients with delusional disorder (DD) and 253 patients with schizophrenia (SC); all patients met DSM-III-R criteria. Because the DD patients were older and had a later age at onset of illness, a sub-sample ...

https://doi.org/10.1176/jnp.8.3.281

Publication date: 01 August 1996

Pages287–292

Studies suggest a high frequency of epileptic auras with intellectual content among epileptic patients with psychopathology and personality disorders. This study compared measures of personality and psychosocial functioning between epileptic patients with ...

https://doi.org/10.1176/jnp.8.3.287

Publication date: 01 August 1996

Pages293–304

The authors examined decision making in HIV patients under slow and rapid information deliveries. Thirteen asymptomatic, HIV-infected (HIV+) subjects with known seroconversion dates and 13 healthy control subjects were instructed to detect the "oddball" ...

https://doi.org/10.1176/jnp.8.3.293

Publication date: 01 August 1996

Pages305–310

This study investigated the stability over time of delays in auditory event-related potentials (ERPs) caused by HIV-1 infection of the brain. ERPs were recorded at two time points from 17 former parenteral drug users (PDUs) and 8 non-PDU control subjects. ...

https://doi.org/10.1176/jnp.8.3.305

Publication date: 01 August 1996

Pages311–317

The authors surveyed 87 adolescent or adult patients with Tourette's syndrome (TS) regarding the presence, characteristics, and functional impact of non-obscene socially inappropriate (SI) behavior. Reported behaviors included insulting others (22%), ...

https://doi.org/10.1176/jnp.8.3.311

Publication date: 01 August 1996

Pages318–323

Retrospective review of affective disturbances in 238 patients with multiple sclerosis (MS) seen over a 6-month period revealed: 1) 51 patients (22%) received pharmacologic treatment for depressive symptoms during or within 4 years of the study period, ...

https://doi.org/10.1176/jnp.8.3.318

Publication date: 01 August 1996

Pages324–334

A retrospective study of 20 patients with mild traumatic brain injury (MTBI) examined brain regions of interest by comparing [18F]-2- deoxyglucose PET, neuropsychological test results, and continuing behavioral dysfunction. Abnormal local cerebral ...

https://doi.org/10.1176/jnp.8.3.324

Publication date: 01 August 1996

Pages335–337

Apo-E genotype was not significantly related to cognitive performance in 157 Alzheimer's disease patients. However, patients homozygous for the epsilon 4 allele appeared most impaired on global cognition but least impaired on language measures. Further ...

https://doi.org/10.1176/jnp.8.3.335

Publication date: 01 August 1996

Pages338–340

Sertraline, a selective serotonin reuptake inhibitor, was used to treat two consecutive cases of genetically confirmed Huntington's disease in which severe irritability and aggressiveness required inpatient admission. The complete cessation of aggressive ...

https://doi.org/10.1176/jnp.8.3.338

Publication date: 01 August 1996

Pages341–346

Seven patients with refractory seizure disorders and neuropsychiatric symptoms believed secondary to felbamate are presented. Five were on concomitant valproic acid (and other agents). Anergia, apathy, bradyphrenia, and increased irritability were ...

https://doi.org/10.1176/jnp.8.3.341

Publication date: 01 August 1996

Pages347–350

Cocaine-induced paranoia (CIP) remains an important drug-induced model of idiopathic paranoia for which no psychophysiologic marker has yet emerged. Measures of pupillary oscillation were able to significantly distinguish a group of abstinent crack ...

https://doi.org/10.1176/jnp.8.3.347

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