The Journal of Neuropsychiatry and Clinical Neurosciences
- Volume 8
- Number 2
- May 1996
Publication date: 01 May 1996
Pages125–138Many neuroimaging studies have implicated the orbital frontal cortex (OFC) in the pathophysiology of obsessive-compulsive disorder. In recent years there have been significant advances in elucidating the anatomical characteristics of the OFC in nonhuman ...
https://doi.org/10.1176/jnp.8.2.125Publication date: 01 May 1996
Pages139–146Seventeen healthy normal volunteers performed three facial recognition tasks while their cerebral blood flow was measured with PET: categorizing faces according to gender, recognizing new faces, and recognizing familiar faces. These tasks activated three ...
https://doi.org/10.1176/jnp.8.2.139Publication date: 01 May 1996
Pages147–152Cavum septi pellucidi (CSP) is a midline developmental anomaly shown to have increased incidence in patients with schizophrenia. The etiology of CSP may involve dysgenesis of the temporal lobes. This study evaluated the pattern of brain changes in three ...
https://doi.org/10.1176/jnp.8.2.147Publication date: 01 May 1996
Pages153–159This study examined the relationship between post-stroke lesion size and location and depressed mood by using data from the multicenter National Stroke Data Bank. For in patients with first-ever cerebral infarction, lesions were characterized by location ...
https://doi.org/10.1176/jnp.8.2.153Publication date: 01 May 1996
Pages160–167The authors describe 9 patients with bipolar affective disorder associated with cerebrovascular lesions. Eight had negative family histories of affective disorders and late age at onset (after age 40) of manic-depressive symptoms. Only one, with positive ...
https://doi.org/10.1176/jnp.8.2.160Publication date: 01 May 1996
Pages168–171Phenylethylamine (PEA), an endogenous neuroamine, increases attention and activity in animals and has been shown to relieve depression in 60% of depressed patients. It has been proposed that PEA deficit may be the cause of a common form of depressive ...
https://doi.org/10.1176/jnp.8.2.168Publication date: 01 May 1996
Pages172–180Rapid-rate transcranial magnetic stimulation (rTMS) was administered to 10 healthy volunteers on different days over the right or left prefrontal cortex, midfrontal cortex, occipital cortex, or cerebellum. Mood (self-rated), reaction time, and hormone ...
https://doi.org/10.1176/jnp.8.2.172Publication date: 01 May 1996
Pages181–185One hundred thirty-seven patients with treated Graves' disease completed a questionnaire pertaining to neuropsychiatric complaints. Psychiatric symptoms, especially anxiety and irritability, were common prior to treatment of hyperthyroidism. These ...
https://doi.org/10.1176/jnp.8.2.181Publication date: 01 May 1996
Pages186–193Aggressive behavior is difficult to capture with most available rating instruments because it occurs with low frequency. The Overt Aggression Scale (OAS) was designed to capture all incidents on a 24-hour basis. To assess its usefulness, the OAS was ...
https://doi.org/10.1176/jnp.8.2.186Publication date: 01 May 1996
Pages194–201This study evaluated whether decrements in peripheral leukocyte counts induced by cyclophosphamide can be conditioned in humans. Ten subjects being treated for multiple sclerosis received four intravenous treatments with cyclophosphamide (unconditioned ...
https://doi.org/10.1176/jnp.8.2.194Publication date: 01 May 1996
Pages202–205The cases of 3 patients with Alzheimer's disease (AD) who had varied outcomes from treatment with tacrine or other palliative drugs illustrate the need to consider the benefits of such agents for each case on an individual basis. In the absence of a cure, ...
https://doi.org/10.1176/jnp.8.2.202Publication date: 01 May 1996
Pages206–208An 81-year-old woman with postmenopausal onset of a bipolar disorder had multiple individual manic and depressive episodes over the span of 31 years. Autopsy disclosed widespread periventricular demyelinated plaques. Although the late age at onset of ...
https://doi.org/10.1176/jnp.8.2.206Publication date: 01 May 1996
Pages209–210The authors report successful ECT treatment of a severely depressed man with genetically confirmed Huntington's disease. He responded well to treatment and showed no abnormal movements or worsening in his cognitive status.
https://doi.org/10.1176/jnp.8.2.209Publication date: 01 May 1996
Pages211–214Male Alzheimer's disease patients, studied with 18-fluoro-2- deoxyglucose positron emission tomography while performing a verbal memory test, showed a right-greater-than-left asymmetry of cortical metabolism that tended to be greater than that in healthy, ...
https://doi.org/10.1176/jnp.8.2.211Dopamine receptor binding predicts clinical and pharmacological potencies of antischizophrenic drugs
Publication date: 01 May 1996
Pages223–226Tritiated haloperidol and tritiated dopamine label postsynaptic dopamine receptors in mammalian brain. Clinical potencies of butyrophenones, phenothiazines, and related drugs correlate closely with their ability to inhibit tritiated haloperidol binding. ...
https://doi.org/10.1176/jnp.8.2.223