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The Journal of Neuropsychiatry and Clinical Neurosciences

  • Volume 8
  • Number 2
  • May 1996

Publication date: 01 May 1996

Pages125–138

Many neuroimaging studies have implicated the orbital frontal cortex (OFC) in the pathophysiology of obsessive-compulsive disorder. In recent years there have been significant advances in elucidating the anatomical characteristics of the OFC in nonhuman ...

https://doi.org/10.1176/jnp.8.2.125

Publication date: 01 May 1996

Pages139–146

Seventeen healthy normal volunteers performed three facial recognition tasks while their cerebral blood flow was measured with PET: categorizing faces according to gender, recognizing new faces, and recognizing familiar faces. These tasks activated three ...

https://doi.org/10.1176/jnp.8.2.139

Publication date: 01 May 1996

Pages147–152

Cavum septi pellucidi (CSP) is a midline developmental anomaly shown to have increased incidence in patients with schizophrenia. The etiology of CSP may involve dysgenesis of the temporal lobes. This study evaluated the pattern of brain changes in three ...

https://doi.org/10.1176/jnp.8.2.147

Publication date: 01 May 1996

Pages153–159

This study examined the relationship between post-stroke lesion size and location and depressed mood by using data from the multicenter National Stroke Data Bank. For in patients with first-ever cerebral infarction, lesions were characterized by location ...

https://doi.org/10.1176/jnp.8.2.153

Publication date: 01 May 1996

Pages160–167

The authors describe 9 patients with bipolar affective disorder associated with cerebrovascular lesions. Eight had negative family histories of affective disorders and late age at onset (after age 40) of manic-depressive symptoms. Only one, with positive ...

https://doi.org/10.1176/jnp.8.2.160

Publication date: 01 May 1996

Pages168–171

Phenylethylamine (PEA), an endogenous neuroamine, increases attention and activity in animals and has been shown to relieve depression in 60% of depressed patients. It has been proposed that PEA deficit may be the cause of a common form of depressive ...

https://doi.org/10.1176/jnp.8.2.168

Publication date: 01 May 1996

Pages172–180

Rapid-rate transcranial magnetic stimulation (rTMS) was administered to 10 healthy volunteers on different days over the right or left prefrontal cortex, midfrontal cortex, occipital cortex, or cerebellum. Mood (self-rated), reaction time, and hormone ...

https://doi.org/10.1176/jnp.8.2.172

Publication date: 01 May 1996

Pages181–185

One hundred thirty-seven patients with treated Graves' disease completed a questionnaire pertaining to neuropsychiatric complaints. Psychiatric symptoms, especially anxiety and irritability, were common prior to treatment of hyperthyroidism. These ...

https://doi.org/10.1176/jnp.8.2.181

Publication date: 01 May 1996

Pages186–193

Aggressive behavior is difficult to capture with most available rating instruments because it occurs with low frequency. The Overt Aggression Scale (OAS) was designed to capture all incidents on a 24-hour basis. To assess its usefulness, the OAS was ...

https://doi.org/10.1176/jnp.8.2.186

Publication date: 01 May 1996

Pages194–201

This study evaluated whether decrements in peripheral leukocyte counts induced by cyclophosphamide can be conditioned in humans. Ten subjects being treated for multiple sclerosis received four intravenous treatments with cyclophosphamide (unconditioned ...

https://doi.org/10.1176/jnp.8.2.194

Publication date: 01 May 1996

Pages202–205

The cases of 3 patients with Alzheimer's disease (AD) who had varied outcomes from treatment with tacrine or other palliative drugs illustrate the need to consider the benefits of such agents for each case on an individual basis. In the absence of a cure, ...

https://doi.org/10.1176/jnp.8.2.202

Publication date: 01 May 1996

Pages206–208

An 81-year-old woman with postmenopausal onset of a bipolar disorder had multiple individual manic and depressive episodes over the span of 31 years. Autopsy disclosed widespread periventricular demyelinated plaques. Although the late age at onset of ...

https://doi.org/10.1176/jnp.8.2.206

Publication date: 01 May 1996

Pages209–210

The authors report successful ECT treatment of a severely depressed man with genetically confirmed Huntington's disease. He responded well to treatment and showed no abnormal movements or worsening in his cognitive status.

https://doi.org/10.1176/jnp.8.2.209

Publication date: 01 May 1996

Pages211–214

Male Alzheimer's disease patients, studied with 18-fluoro-2- deoxyglucose positron emission tomography while performing a verbal memory test, showed a right-greater-than-left asymmetry of cortical metabolism that tended to be greater than that in healthy, ...

https://doi.org/10.1176/jnp.8.2.211

Publication date: 01 May 1996

Pages223–226

Tritiated haloperidol and tritiated dopamine label postsynaptic dopamine receptors in mammalian brain. Clinical potencies of butyrophenones, phenothiazines, and related drugs correlate closely with their ability to inhibit tritiated haloperidol binding. ...

https://doi.org/10.1176/jnp.8.2.223

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