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Published Online: 17 June 2011

Points to Remember

Mental Illness Is a Brain Disorder

"Multimodal" techniques using EEG and functional magnetic resonance imaging are providing a comprehensive picture of the structural, functional, and temporal connectivity in the brain.
Medications, cognitive-behavior therapy and other interventions appear to affect different parts of brain circuitry involved in mental disorders.

Mental Disorders Are Developmental Disorders

Onset of mental illness is almost entirely before the age of 25.
Emerging evidence shows that ADHD is a developmental disorder characterized by delay of cortical maturation.

Mental Disorders Result From Complex Genetic Risk Plus Experiential Factors

Genetics of mental illness are characterized by very rare but potent variations.
These rare variations result in changes in brain circuitry that, in complex interaction with environmental influences, result in many pathways to phenotypes of mental illness.

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Published online: 17 June 2011
Published in print: June 17, 2011

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