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Published Online: June 1960

TREATMENT OF CHRONIC SCHIZOPHRENICS WITH LIOTHYRONINE (L-TRIIODOTHYRONINE)

E. J. TOLAN, B. KOVITZ, and LOWELL DILLONAuthors Info & Affiliations

Publication: American Journal of Psychiatry

Volume 116, Number 12

https://doi.org/10.1176/ajp.116.12.1111

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Abstract

Half of the group of 24 showed temporary changes. These changes were maximal at the peak doses, either in the direction of decreased depression and withdrawal (8 cases) or increased restlessness and tension (4 cases). These changes were not lasting, and as the medication was decreased, the group as a whole returned to its original level. The temporary periods of improvement occurred in a peculiar cyclic pattern, lasting from a few days to a few weeks at a time.

In higher doses the drug was accompanied by changes in the mood and activity of chronic schizophrenic patients, but did not bring about a lasting or dependable improvement in psychiatric status or hospital adjustment. The use of liothyronine in psychiatric disorders must still be considered in experimental stage.

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Information & Authors

Information

Published In

American Journal of Psychiatry

Volume 116 • Number 12 • June 1960

Pages: 1111 - 1112

PubMed: 13838677

History

Published in print: June 1960

Published online: 1 April 2006

Authors

Details

E. J. TOLAN

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B. KOVITZ

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LOWELL DILLON

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Resident Psychiatrist, Columbus State Hospital, Columbus, Ohio.

Clinical Director, Columbus State Hospital, Columbus, Ohio.

Superintendent, Columbus State Hospital, Columbus, Ohio.

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TREATMENT OF CHRONIC SCHIZOPHRENICS WITH LIOTHYRONINE (L-TRIIODOTHYRONINE)

Abstract

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