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Published Online: October 1965

PHYSIOLOGIC TREATMENT OF DEPRESSIVE REACTIONS: A PILOT STUDY

Publication: American Journal of Psychiatry

Abstract

No treatment has yet been devised that can cure all forms of depression or even all patients with any single type of depressive reaction. This pilot study revealed that prednisone was effective in ameliorating only the components of affective disorder in neurotic- and psychotic-depressives and in schizo-affectives. Because of the marked effects in every subject, the use of sequential statistics to analyze the clinical ratings of depression yielded evidence of improvement at the 99% level of confidence with only 4 cases in each of the 3 categories. Further clinical studies of larger populations and variable treatment combinations now appear warranted.

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Go to American Journal of Psychiatry
Go to American Journal of Psychiatry
American Journal of Psychiatry
Pages: 457 - 458
PubMed: 5889791

History

Published in print: October 1965
Published online: 1 April 2006

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HOWARD D. KURLAND
Chief, Psychiatric Service, Veterans Administration Research Hospital, Chicago, Ill.

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