Drug-Induced Extrapyramidal Symptoms and Their Relations to Clinical Efficacy

CHING-PIAO CHIEN and ALBERTO DIMASCIOAuthors Info & Affiliations

Publication: American Journal of Psychiatry

Volume 123, Number 12

https://doi.org/10.1176/ajp.123.12.1490

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Abstract

Various theories have been proposed relating classes of drug-induced extrapyramidal symptoms to the therapeutic actions of these drugs. But contradictory conclusions have been drawn from basically similar sets of observations; the literature on the topic is fraught with confusion and equivocal results. The authors suggest reasons for the past confusion and urge that future studies be designed with adequate controls and methodological sophistication.

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Information & Authors

Information

Published In

American Journal of Psychiatry

Volume 123 • Number 12 • June 1967

Pages: 1490 - 1498

PubMed: 5337751

History

Published in print: June 1967

Published online: 1 April 2006

Authors

Affiliations

CHING-PIAO CHIEN

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ALBERTO DIMASCIO

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Clinical Instructor in Psychiatry, Tufts University School of Medicine, Boston, Mass., and Staff Psychiatrist, Boston State Hospital

Director of the Psychopharmacology Research Laboratory, Massachusetts Mental Health Center, Harvard Medical School, and Research Associate, Harvard Medical School

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Drug-Induced Extrapyramidal Symptoms and Their Relations to Clinical Efficacy

Abstract

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