Establishment of Diagnostic Validity in Psychiatric Illness: Its Application to Schizophrenia

ELI ROBINS and SAMUEL B. GUZEAuthors Info & Affiliations

Publication: American Journal of Psychiatry

Volume 126, Number 7

https://doi.org/10.1176/ajp.126.7.983

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Abstract

A method for achieving diagnostic validity in psychiatric illness is described, consisting of five phases: clinical description, laboratory study, exclusion of other disorders, follow-up study, and family study. The method was applied in this paper to patients with the diagnosis of schizophrenia, and it was shown by follow-up and family studies that poor prognosis cases can be validly separated clinically from good prognosis cases. The authors conclude that good prognosis "schizophrenia" is not mild schizophrenia, but a different illness.

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Information & Authors

Information

Published In

American Journal of Psychiatry

Volume 126 • Number 7 • January 1970

Pages: 983 - 987

PubMed: 5409569

History

Published in print: January 1970

Published online: 1 April 2006

Authors

Affiliations

ELI ROBINS

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SAMUEL B. GUZE

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Wallace Renard professor and head of the department, psychiatrist-in-chief, Barnes and Renard Hospitals, department of psychiatry, Washington University School of Medicine, 4940 Audubon Ave., St. Louis, Mo. 63110

Professor, associate psychiatrist, department of psychiatry, Washington University School of Medicine, 4940 Audubon Ave., St. Louis, Mo. 63110

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Establishment of Diagnostic Validity in Psychiatric Illness: Its Application to Schizophrenia

Abstract

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