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Research Article
Published Online: October 1980

Neuroloeptic effect on desipramine steady-state plasma concentratins

Publication: American Journal of Psychiatry

Abstract

The authors examined the effect of neuroleptic drugs on desipramine steady-state plasma concentration in 30 patients who received similar milligram per kilogram doses of desipramine. Fifteen of these patients also received a neuroloeptic drug and had desipramine plasma levels twice that of the 15 patients who received dispiramine alone. The authros discuss the implications of the magnitude of this difference for therapeutic response and incidence of side effects.

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Go to American Journal of Psychiatry
Go to American Journal of Psychiatry
American Journal of Psychiatry
Pages: 1232 - 1234
PubMed: 6106391

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Published in print: October 1980
Published online: 1 April 2006

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