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Research Article
Published Online: April 1984

CSF 5-hydroxyindoleacetic acid levels in suicidal schizophrenic patients

Publication: American Journal of Psychiatry

Abstract

Concentrations of 5-hydroxyindoleacetic acid (5-HIAA) in the lumbar CSF were measured in a group of suicidal schizophrenic patients and in a matched group of nonsuicidal schizophrenic patients. The suicidal group had a significantly lower level. This finding is consistent with reports of low levels of CSF 5-HIAA in suicidal patients with other psychiatric diagnoses and suggests that low CSF 5-HIAA may be a generalized marker of aggressive behavior against the self and others.

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Go to American Journal of Psychiatry
Go to American Journal of Psychiatry
American Journal of Psychiatry
Pages: 566 - 569
PubMed: 6199986

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Published in print: April 1984
Published online: 1 April 2006

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