American Journal of Psychiatry
- Volume 144
- Number 10
- October 1987
Publication date: 01 October 1987
Pages1253–1262The dexamethasone suppression test (DST) has had unprecedented evaluation among biological tests proposed for clinical use in psychiatry. It is hypothesized to reflect pathophysiologic changes at the CNS level. The sensitivity of the DST (rate of a ...
https://doi.org/10.1176/ajp.144.10.1253Publication date: 01 October 1987
Pages1263–1270Multidisciplinary studies of adulthood have revolutionized thinking about developmental processes during the second half of life. These ideas are just beginning to be integrated with clinical theory and practice. The elaboration of the interface between ...
https://doi.org/10.1176/ajp.144.10.1263Publication date: 01 October 1987
Pages1271–1276Thirty-nine patients with chronic schizophrenia for whom hospitalization was clinically indicated received haloperidol for 4 to 6 weeks in a standardized dose schedule. Responders were compared with nonresponders for family history, baseline symptom ...
https://doi.org/10.1176/ajp.144.10.1271Publication date: 01 October 1987
Pages1277–1282The authors studied the relationship between lateral cerebral ventricular size and regional cerebral blood flow during mental activation in 30 patients with schizophrenia. Patients with large ventricles had diffusely lower cortical gray matter blood flow ...
https://doi.org/10.1176/ajp.144.10.1277Publication date: 01 October 1987
Pages1283–1287The authors used structured diagnostic interviews to assess the lifetime prevalence of psychiatric disorders, by DSM-III criteria, among 70 women: 51 outpatients with active bulimia and 19 nonpatient subjects with remitted bulimia. Comparison groups ...
https://doi.org/10.1176/ajp.144.10.1283Publication date: 01 October 1987
Pages1288–1292Rates of mental illness were examined in 30 creative writers, 30 matched control subjects, and the first-degree relatives of both groups. The writers had a substantially higher rate of mental illness, predominantly affective disorder, with a tendency ...
https://doi.org/10.1176/ajp.144.10.1288Publication date: 01 October 1987
Pages1293–1297Psychotherapy, especially the intensive variety, has been put under considerable adverse pressure by changes in the economics of medicine and psychiatry. The dominance of third-party rather than out-of-pocket payment for services raises questions about ...
https://doi.org/10.1176/ajp.144.10.1293Publication date: 01 October 1987
Pages1301–1305Sixteen depressed patients with seasonal affective disorder participated in a double-blind crossover study comparing the antidepressant effects of 2 hours of early morning and 2 hours of early afternoon therapy with bright light. They responded equally ...
https://doi.org/10.1176/ajp.144.10.1301Publication date: 01 October 1987
Pages1306–1309The inability to determine which schizophrenic patients do not require maintenance medication is a significant gap in current knowledge. This report describes 23 largely chronic DSM-III schizophrenic patients who, after a period of inpatient treatment, ...
https://doi.org/10.1176/ajp.144.10.1306Publication date: 01 October 1987
Pages1310–1312The authors studied psychiatric complications of disulfiram use in 605 alcoholic patients. The subjects were assigned to one of three treatment groups: a 250-mg disulfiram group (N = 202), a 1-mg disulfiram group (N = 204) to control for the fear of the ...
https://doi.org/10.1176/ajp.144.10.1310Publication date: 01 October 1987
Pages1313–1316Somatostatin-like immunoreactivity was measured in the CSF of 12 patients with Alzheimer's disease, 15 age-matched control subjects, and 20 older depressed subjects. Patients with dementia or depression were found to have lower CSF somatostatin ...
https://doi.org/10.1176/ajp.144.10.1313Publication date: 01 October 1987
Pages1317–1319The authors administered infusions of lactate intravenously to seven patients with a DSM-III diagnosis of posttraumatic stress disorder, six of whom also met DSM-III criteria for panic disorder. The lactate infusions resulted in flashbacks in all seven ...
https://doi.org/10.1176/ajp.144.10.1317Publication date: 01 October 1987
Pages1320–1323The authors evaluated 24 outpatients with panic disorder by means of the afternoon continuous test for cortisol and the 1-mg dexamethasone suppression test (DST) and compared the results with those of 38 outpatients with major depressive disorder and 61 ...
https://doi.org/10.1176/ajp.144.10.1320Publication date: 01 October 1987
Pages1324–1327Cyclic adenosine 3',5'-monophosphate (cAMP) signal transduction was examined in lymphocytes and platelets obtained from patients with posttraumatic stress disorder. Intact lymphocytes from the posttraumatic patients (N = 10) showed significantly lower ...
https://doi.org/10.1176/ajp.144.10.1324Publication date: 01 October 1987
Pages1327–1330Patients under evaluation for cardiac transplant surgery were seen for routine psychiatric diagnosis and treatment. Of 35 patients with idiopathic cardiomyopathy, 83% (N = 29) had definite or probable panic disorder. Of 25 patients with postinfarction ...
https://doi.org/10.1176/ajp.144.10.1327Publication date: 01 October 1987
Pages1331–1334Psychiatrists in Australia were asked to recommend treatments for several anxiety and somatoform disorders. In previous surveys they had agreed about the preferred treatments for schizophrenia and major affective disorder but not about treatments for "...
https://doi.org/10.1176/ajp.144.10.1331Publication date: 01 October 1987
Pages1335–1337Fourteen drug-free male patients with schizophrenia had a smaller and slower prolactin response to 0.5 mg of intravenous haloperidol than 14 normal age- and sex-matched control subjects. This finding supports the presence of dopaminergic dysfunction in ...
https://doi.org/10.1176/ajp.144.10.1335Publication date: 01 October 1987
Pages1337–1339A once-a-week outpatient therapy group was designed for schizophrenic substance abusers. Over 1 year, the group members (including dropouts) had a marked decrease in days of hospitalization.
https://doi.org/10.1176/ajp.144.10.1337Publication date: 01 October 1987
Pages1340–1342The antipsychotic potency of the partial opiate agonist buprenorphine was evaluated in 10 neuroleptic-free schizophrenic patients suffering from frequent hallucinations, delusions, and severe formal thought disorders. Buprenorphine had a pronounced ...
https://doi.org/10.1176/ajp.144.10.1340Publication date: 01 October 1987
Pages1342–1344Major depression with psychotic features, dementia, and focal neurologic abnormalities appeared in a Haitian man without AIDS or other syndromes of immune compromise. Neurologic evaluation, including brain biopsy, was nondiagnostic, but CSF culture ...
https://doi.org/10.1176/ajp.144.10.1342Publication date: 01 October 1987
Pages1344–1346In an 18-month prospective assessment of 679 hospitalized, neuroleptic- treated patients, the authors, using previously defined operational criteria, diagnosed neuroleptic malignant syndrome in six cases (0.9%). This supports their earlier finding that ...
https://doi.org/10.1176/ajp.144.10.1344Publication date: 01 October 1987
Pages1347–1348The authors report on four patients with disabling bowel obsessions who responded to tricyclic antidepressant medication despite the absence of depressive symptoms. The relationship of this symptom constellation to DSM-III obsessive-compulsive disorder ...
https://doi.org/10.1176/ajp.144.10.1347Publication date: 01 October 1987
Pages1349–1350The author studied 18 heroin addicts who had been maintained on 80 mg/day of methadone and who abused drugs or alcohol. His findings suggest that in some cases of aberrant methadone metabolism, the dose can be raised to achieve plasma concentrations ...
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