This is the second of two articles on the conceptual and methodological problems involved in comparing the effectiveness of drugs and psychotherapy in the treatment of mental disorders. Part II focuses on differences between psychotherapy and ...

https://doi.org/10.1176/ajp.145.9.1070

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A multidimensional approach to the genetics of schizophrenia

Publication date: 01 September 1988

Pages1077–1083

To determine which dimensions of psychopathology are associated with a greater liability to develop schizophrenia, the authors examined the case histories of 151 monozygotic probands from five twin studies. Proband twins from pairs concordant for ...

https://doi.org/10.1176/ajp.145.9.1077

Comparison of MRI and CT scans in a group of psychiatric patients

Publication date: 01 September 1988

Pages1084–1088

The authors compared the results of computerized tomography (CT) and magnetic resonance imaging (MRI) scans of 16 psychotic patients with various diagnoses whose neurologic examinations suggested structural brain abnormalities. Blind readings showed a ...

https://doi.org/10.1176/ajp.145.9.1084

Neuroanatomical abnormalities in obsessive-compulsive disorder detected with quantitative X-ray computed tomography

Publication date: 01 September 1988

Pages1089–1093

New brain imaging techniques may provide evidence for a biological basis for severe psychiatric disorders. The authors used quantitative X- ray computed tomography (CT) to analyze the brain volume of 10 male patients with severe primary obsessive-...

https://doi.org/10.1176/ajp.145.9.1089

Anterior pituitary, adrenal, and gonadal hormones during cocaine withdrawal

Publication date: 01 September 1988

Pages1094–1098

Plasma luteinizing hormone (LH), prolactin, testosterone, and cortisol levels were determined in 16 patients after hospital admission for cocaine abuse, during the course of 4 weeks of hospitalization, and before discharge. Hyperprolactinemia was found at ...

https://doi.org/10.1176/ajp.145.9.1094

Bedside differentiation of depressive pseudodementia from dementia

Publication date: 01 September 1988

Pages1099–1103

The authors analyzed the pretreatment clinical presentations of 14 patients with depressive pseudodementia and 28 patients with primary degenerative dementia as measured by the Mini-Mental State, the Blessed Dementia Rating Scale, and the Hamilton Rating ...

https://doi.org/10.1176/ajp.145.9.1099

Lack of efficacy of carbamazepine in the treatment of panic disorder

Publication date: 01 September 1988

Pages1104–1109

The authors conducted a controlled study of carbamazepine in the treatment of 14 patients with panic disorder. Although there was a statistically significant reduction in symptoms of anxiety on several measures, only one of the patients was judged to have ...

https://doi.org/10.1176/ajp.145.9.1104

S-adenosylmethionine treatment of depression: a controlled clinical trial

Publication date: 01 September 1988

Pages1110–1114

The antidepressant properties of S-adenosylmethionine, an endogenous methyl donor, were studied in inpatients who met the DSM-III criteria for major depression. Nine patients given intravenous S- adenosylmethionine and nine given low oral doses of ...

https://doi.org/10.1176/ajp.145.9.1110

A randomized clinical trial of inpatient family intervention, III: Effects at 6-month and 18-month follow-ups

Publication date: 01 September 1988

Pages1115–1121

This paper focuses on the follow-up results of a randomized clinical trial of inpatient family intervention (IFI) that emphasized psychoeducation. Results for the sample of 169 psychiatric patients suggested that adding family treatment to standard ...

https://doi.org/10.1176/ajp.145.9.1115

Four-year evaluation of a psychiatric clerkship: 1982-1986

Publication date: 01 September 1988

Pages1122–1126

The authors describe a psychiatric clerkship organized to achieve goals relevant to all medical students, regardless of their future specialty choice. The clerkship had been in place for 8 years in 1986, and standardized program evaluations were available ...

https://doi.org/10.1176/ajp.145.9.1122

Personality features of obsessive-compulsive disorder

Publication date: 01 September 1988

Pages1127–1129

The authors evaluated personality dysfunction in 23 patients with primary obsessive-compulsive disorder and an age- and sex-matched group of patients with major depressive disorder. There were no significant differences between the two patient groups with ...

https://doi.org/10.1176/ajp.145.9.1127

A new and timely delusion: the complaint of having AIDS

Publication date: 01 September 1988

Pages1130–1132

Delusions presented by patients with psychiatric disorders are often a combination of psychopathology and current events. The authors present three cases that document the delusion of having acquired immune deficiency syndrome (AIDS) in patients who were ...

https://doi.org/10.1176/ajp.145.9.1130

Twenty-four-hour profiles of body temperature and plasma TSH in bipolar patients during depression and during remission and in normal control subjects

Publication date: 01 September 1988

Pages1133–1137

The 24-hour patterns of body temperature and plasma thyrotropin (TSH) were measured in eight bipolar patients in both depressed and recovered (after 3 weeks of treatment) states and in eight normal control subjects. Clear circadian patterns were detected ...

https://doi.org/10.1176/ajp.145.9.1133

Placebo response in panic disorder

Publication date: 01 September 1988

Pages1138–1140

Of 43 patients with panic disorder or agoraphobia with panic attacks who took placebo for 8 weeks in two double-blind studies, one in four markedly improved. Those with consistently normal dexamethasone suppression test results were significantly more ...

https://doi.org/10.1176/ajp.145.9.1138

A study of filicidal men

Publication date: 01 September 1988

Pages1141–1144

Twelve filicidal men were examined on a forensic psychiatric service. The majority suffered from severe mental impairments due to psychosis, neurological disorders, substance abuse, or mental retardation. Most of the filicidal acts committed by these ...

https://doi.org/10.1176/ajp.145.9.1141

The relationship of presenting complaints to the use of psychiatric services in a low-income group

Publication date: 01 September 1988

Pages1145–1148

The presenting complaints of 503 subjects who contacted a mental health clinic serving an inner-city, low-income group were classified into mental state, physical functioning, social relations, and social performance. The authors examined the relationship ...

https://doi.org/10.1176/ajp.145.9.1145

DSM-III personality disorders and the outcome of treated panic disorder

Publication date: 01 September 1988

Pages1149–1152

Fifty-two patients with panic disorder who had been receiving active benzodiazepine treatment for 8 weeks were assessed by using the outcome measures of spontaneous and situational panic attacks, scores on the Hamilton scales for anxiety and for ...

https://doi.org/10.1176/ajp.145.9.1149

DST results in nonpsychotic depressed outpatients

Publication date: 01 September 1988

Pages1153–1156

In two studies using the dexamethasone suppression test (DST) to evaluate the efficacy of newer antidepressants in depressed outpatients, the authors found a DST nonsuppression rate of 13% (11 of 86 patients). Thirty-three of the DST suppressors received ...

https://doi.org/10.1176/ajp.145.9.1153