American Journal of Psychiatry
- Volume 150
- Number 9
- September 1993
Article
Publication date: 01 September 1993
Pages1309–1314The changes that have taken place in medicine over the past few decades have challenged our views about the responsibilities and obligations of those providing health care and about their relationships with their patients. The demands brought by ...
https://doi.org/10.1176/ajp.150.9.1309Publication date: 01 September 1993
Pages1315–1324OBJECTIVE: The author reviews current wisdom concerning the rates and mechanisms of intrafamilial components of intergenerational transmission of child abuse and illustrates the unreliability of basic data and of assumptions made by reviewers and partisan ...
https://doi.org/10.1176/ajp.150.9.1315Publication date: 01 September 1993
Pages1325–1336OBJECTIVE: The cortical-striatal-thalamic circuit modulates cognitive processing and thus may be involved in the cognitive dysfunction in schizophrenia. The imaging of metabolic rate in the structures making up this circuit could reveal the correlates of ...
https://doi.org/10.1176/ajp.150.9.1325Publication date: 01 September 1993
Pages1337–1342OBJECTIVE: Clozapine is the only compound proven to be effective in the 20% of schizophrenic patients refractory to treatment with conventional neuroleptics. Although its mechanism of action has not been elucidated, clozapine appears, in contrast to most ...
https://doi.org/10.1176/ajp.150.9.1337Publication date: 01 September 1993
Pages1343–1348OBJECTIVE: Previous studies in schizophrenia have identified abnormalities involving the basal ganglia, but the contribution of neuroleptics to the motor system abnormalities in schizophrenia is usually a confounding factor. This study addressed the issue ...
https://doi.org/10.1176/ajp.150.9.1343Publication date: 01 September 1993
Pages1349–1354OBJECTIVE: To date, the literature has provided no standardized, replicable method for establishing illness onset. The authors describe a method for dating the first appearance of prodromal signs of psychotic illness, the emergence of an acute episode, ...
https://doi.org/10.1176/ajp.150.9.1349Publication date: 01 September 1993
Pages1355–1362OBJECTIVE: This study was designed to ascertain the degree and specificity of cognitive impairments in patients with schizophrenia and patients with affective disorders. METHOD: Cognitive function was assessed with a neuropsychological test battery in ...
https://doi.org/10.1176/ajp.150.9.1355Publication date: 01 September 1993
Pages1363–1367OBJECTIVE: Family studies have demonstrated a higher rate of schizoid personality in the families of probands with schizophrenia and a higher rate of paranoid personality in the families of probands with delusional disorder. The authors sought to ...
https://doi.org/10.1176/ajp.150.9.1363Publication date: 01 September 1993
Pages1368–1373OBJECTIVE: The authors examined associations between patient-related characteristics and assaultiveness on six different psychiatric wards to determine 1) the relative contributions of demographic, disorder- related, and diagnostic variables to prediction ...
https://doi.org/10.1176/ajp.150.9.1368Publication date: 01 September 1993
Pages1374–1379OBJECTIVE: The apparent accuracy of predictions of assaultive behavior in psychiatric inpatients varies substantially, depending on the method used to study the prediction. The authors explored the effects of different measures and sampling strategies on ...
https://doi.org/10.1176/ajp.150.9.1374Publication date: 01 September 1993
Pages1380–1385OBJECTIVE: Previous studies have reported seasonal or monthly variation in suicide. The present study was conducted in order to determine seasonality and other significant rhythms in violent and nonviolent suicide, alone and together, and homicide. METHOD:...
https://doi.org/10.1176/ajp.150.9.1380Publication date: 01 September 1993
Pages1386–1391OBJECTIVE: Careful assessment of research subjects is important because the inclusion of subjects who manifest psychopathology and significant substance abuse in normal comparison groups will decrease statistical and experimental power. The current study ...
https://doi.org/10.1176/ajp.150.9.1386Publication date: 01 September 1993
Pages1392–1397OBJECTIVE: The proportion of women in leadership positions in academic psychiatry has not kept pace with the increase in the number of women entering the field. This study examines differences in career activities between women and men who graduated from ...
https://doi.org/10.1176/ajp.150.9.1392Publication date: 01 September 1993
Pages1398–1403OBJECTIVE: This study sought to evaluate the existence and implications of familial aggregation of emotional and behavioral problems of childhood in a general population sample. METHOD: The children included in the study were chosen with the use of a ...
https://doi.org/10.1176/ajp.150.9.1398Article
Publication date: 01 September 1993
Pages1405–1407OBJECTIVE: The authors studied the effects of vitamin E treatment of tardive dyskinesia; earlier studies have produced contradictory results. METHOD: Twenty-eight patients with tardive dyskinesia were treated in a double-blind, parallel-group comparison ...
https://doi.org/10.1176/ajp.150.9.1405Publication date: 01 September 1993
Pages1408–1410Levels of CSF fluid interleukin-2, but not interleukin-1 alpha, were found to be higher in 10 neuroleptic-free schizophrenic patients than in 10 healthy subjects matched for sex and age. Because interleukin-2 increases dopaminergic neurotransmission and ...
https://doi.org/10.1176/ajp.150.9.1408Publication date: 01 September 1993
Pages1411–1414OBJECTIVE: This study used eye movement tests to examine whether frontal lobe dysfunction is present in delusional disorder. METHOD: Smooth pursuit and voluntary saccadic eye movements of 15 delusional patients, 40 schizophrenic patients, and 40 normal ...
https://doi.org/10.1176/ajp.150.9.1411Publication date: 01 September 1993
Pages1415–1416Thirteen treatment-refractory schizophrenic patients participated in a haloperidol reduction study. Two of the subjects were unable to tolerate medication reduction. These subjects were comparable to the other patients in terms of initial clinical ...
https://doi.org/10.1176/ajp.150.9.1415Publication date: 01 September 1993
Pages1417–1419Nineteen patients with late luteal phase dysphoric disorder (LLPDD) and 11 healthy comparison subjects underwent a 3-month crossover trial of bright (more than 2500 lux) white morning, bright white evening, and placebo dim (less than 10 lux) red evening ...
https://doi.org/10.1176/ajp.150.9.1417Article
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