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American Journal of Psychiatry

  • Volume 152
  • Number 12
  • December 1995

Publication date: 01 December 1995

Pages1705–1713

OBJECTIVE: The author's goal was to explore the historical, political, and social forces that have played a major role in the acceptance of the idea of trauma as a cause of the specific symptoms of posttraumatic stress disorder (PTSD) and to discuss the ...

https://doi.org/10.1176/ajp.152.12.1705

Publication date: 01 December 1995

Pages1714–1720

OBJECTIVE: Epidemiologic studies have reported an association between prenatal exposure to influenza and adult schizophrenia. The authors studied this association in individual patients with schizophrenia and also investigated the relationship of ...

https://doi.org/10.1176/ajp.152.12.1714

Publication date: 01 December 1995

Pages1721–1723

OBJECTIVE: Neuroimaging studies have provided robust evidence that schizophrenia is associated with structural brain abnormalities. However, the underlying pathophysiology of these changes is still unknown. By evaluating brain morphology early in the ...

https://doi.org/10.1176/ajp.152.12.1721

Publication date: 01 December 1995

Pages1724–1729

OBJECTIVE: This study assessed the prevalence of extrapyramidal signs and spontaneous dyskinesia in neuroleptic-naive, first-episode schizophrenic patients and examined the clinical correlates. METHOD: In a prospective study of the psychobiology of ...

https://doi.org/10.1176/ajp.152.12.1724

Publication date: 01 December 1995

Pages1730–1736

OBJECTIVE: This study was undertaken to assess the relationships among CSF concentrations of substrates of mitochondrial energy metabolism, neuroleptic medication, and neurological side effects. METHOD: CSF was obtained from 25 patients with schizophrenia;...

https://doi.org/10.1176/ajp.152.12.1730

Publication date: 01 December 1995

Pages1737–1742

OBJECTIVE: To test the hypothesis that there is a link between the memory deficit associated with schizophrenia and an impairment of consciousness, an experiential approach was used to assess recognition memory and awareness in schizophrenic patients and ...

https://doi.org/10.1176/ajp.152.12.1737

Publication date: 01 December 1995

Pages1743–1748

OBJECTIVE: This study investigated acute and nonacute brief psychoses. On the basis of previous work, the authors proposed that 1) acute brief psychoses occur predominantly in females, 2) they often do not conform to the diagnoses of DSM-III-R, 3) they ...

https://doi.org/10.1176/ajp.152.12.1743

Publication date: 01 December 1995

Pages1749–1756

OBJECTIVE: The authors sought to identify risk factors for rehospitalization in a seriously mentally ill population, focusing on factors that have the potential to be modified through community-based interventions. METHOD: A case-control design was used ...

https://doi.org/10.1176/ajp.152.12.1749

Publication date: 01 December 1995

Pages1757–1764

OBJECTIVE: Previous longitudinal studies of age-related memory loss have focused on objective neuropsychological measures that predict subsequent cognitive change, yet brain metabolic function, self- perception of memory loss, and other measures may also ...

https://doi.org/10.1176/ajp.152.12.1757

Publication date: 01 December 1995

Pages1765–1770

OBJECTIVE: The authors investigated the efficacy and safety of fluoxetine in the treatment of winter seasonal affective disorder. METHOD: Sixty-eight outpatients who met the DSM-III-R criteria for recurrent major depressive episodes, seasonal (winter) ...

https://doi.org/10.1176/ajp.152.12.1765

Publication date: 01 December 1995

Pages1771–1775

OBJECTIVE: Evidence suggests that the neuropathology of Huntington's disease, a neuropsychiatric disorder due to a mutation on chromosome 4, results from excessive activation of glutamate-gated ion channels, which kills neurons by oxidative stress. ...

https://doi.org/10.1176/ajp.152.12.1771

Publication date: 01 December 1995

Pages1776–1781

OBJECTIVE: This study examined the relationship of the somatic symptoms fatigue and insomnia with indicators of both psychiatric disturbance and HIV disease severity. METHOD: Study participants were 98 asymptomatic HIV-infected and 71 uninfected ...

https://doi.org/10.1176/ajp.152.12.1776

Publication date: 01 December 1995

Pages1782–1787

OBJECTIVE: Considerable evidence suggests that low concentrations of 5- hydroxyindoleacetic acid (5-HIAA) in CSF are associated with a history of aggressive behavior in both human and nonhuman primates. The purpose of this investigation was to examine the ...

https://doi.org/10.1176/ajp.152.12.1782

Publication date: 01 December 1995

Pages1788–1792

OBJECTIVE: This study sought to document the prevalence of dissociative experiences in adult female inpatients with borderline personality disorder and to explore the relationship between dissociation, self- mutilation, and childhood abuse history. METHOD:...

https://doi.org/10.1176/ajp.152.12.1788

Publication date: 01 December 1995

Pages1793–1799

OBJECTIVE: Since some symptoms are shared by both attention deficit hyperactivity disorder (ADHD) and comorbid psychiatric conditions, it is possible that a diagnosis of ADHD is an artifact of the overlapping symptoms. This article focuses on the ...

https://doi.org/10.1176/ajp.152.12.1793

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Publication date: 01 December 1995

Pages1801–1803

OBJECTIVE: The authors tested the hypothesis that the regional distribution of cerebral vasculature is anomalous in schizophrenia. METHOD: Dynamic susceptibility contrast magnetic resonance imaging was used to evaluate cerebral blood volume in the right ...

https://doi.org/10.1176/ajp.152.12.1801

Publication date: 01 December 1995

Pages1804–1806

OBJECTIVE: The authors evaluated the interrater reliability of ratings of bizarre delusions, addressing limitations of previous studies. METHOD: Fifty randomly selected psychiatrists rated bizarre delusions in 30 case vignettes adapted from a previous ...

https://doi.org/10.1176/ajp.152.12.1804

Publication date: 01 December 1995

Pages1807–1809

OBJECTIVE: The aim of this study was to compare levels of CSF somatostatin (somatotropin release-inhibiting factor) in drug-free patients with different major psychiatric disorders. METHOD: CSF somatostatin concentrations were measured in 66 drug-free ...

https://doi.org/10.1176/ajp.152.12.1807

Publication date: 01 December 1995

Pages1810–1811

OBJECTIVE: The authors explored the prevalence and predictors of nonresponse to reinstituted lithium prophylaxis in bipolar patients who had relapsed after discontinuation of successful lithium treatment. METHOD: The study was conducted with 54 bipolar ...

https://doi.org/10.1176/ajp.152.12.1810

Publication date: 01 December 1995

Pages1812–1814

OBJECTIVE: The authors assessed the efficacy of clozapine monotherapy for adults with treatment-resistant obsessive-compulsive disorder. METHOD: Twelve adults with refractory obsessive-compulsive disorder participated in a 10-week, open-label, systematic ...

https://doi.org/10.1176/ajp.152.12.1812

Publication date: 01 December 1995

Pages1815–1818

OBJECTIVE: The purpose of this study was to examine the relationships among cumulative lifetime trauma, recent stressful events, and presence and severity of current posttraumatic stress disorder (PTSD) symptoms in Holocaust survivors and nonexposed ...

https://doi.org/10.1176/ajp.152.12.1815

Publication date: 01 December 1995

Pages1819–1820

OBJECTIVE: To explore dopaminergic mechanisms in alcohol dependence, the authors measured plasma homovanillic acid (HVA) in recently detoxified alcohol-dependent men. METHOD: Plasma HVA was measured in 83 male patients with a diagnosis of alcohol ...

https://doi.org/10.1176/ajp.152.12.1819

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