American Journal of Psychiatry
- Volume 152
- Number 3
- March 1995
Publication date: 01 March 1995
Pages332–340OBJECTIVE: Although alcoholism is one of the most common psychiatric diagnoses, understanding of its pathophysiology remains poor. Accumulating evidence suggests that neurophysiological and pathological effects of ethanol are mediated to a considerable ...
https://doi.org/10.1176/ajp.152.3.332Publication date: 01 March 1995
Pages341–351OBJECTIVE: The specific brain regions involved in the normal emotional states of transient sadness or happiness are poorly understood. The authors therefore sought to determine if H2(15)O positron emission tomography (PET) might demonstrate changes in ...
https://doi.org/10.1176/ajp.152.3.341Publication date: 01 March 1995
Pages352–357OBJECTIVE: The authors examined the overall health care costs associated with depression and anxiety among primary care patients. METHOD: Of 2,110 consecutive primary care patients in a health maintenance organization, 1,962 were screened with the 12-item ...
https://doi.org/10.1176/ajp.152.3.352Publication date: 01 March 1995
Pages358–364OBJECTIVE: The two purposes of this study were to provide a comprehensive description of the clinical features of patients who presented to an intake psychiatric setting with major depression and alcohol dependence and to determine which clinical features ...
https://doi.org/10.1176/ajp.152.3.358Publication date: 01 March 1995
Pages365–372OBJECTIVE: This 5-year follow-up study was designed to explore the factors that might lead to alcoholism in patients with bipolar disorder. METHOD: The authors studied patients with bipolar illness (70 with alcoholism and 161 without), their relatives, ...
https://doi.org/10.1176/ajp.152.3.365Publication date: 01 March 1995
Pages373–378OBJECTIVE: This study examined demographic, sociocultural, familial background, and health-related risk factors for major depression in a community sample of African Americans. METHOD: Data came from a probability sample of 865 urban African American ...
https://doi.org/10.1176/ajp.152.3.373Publication date: 01 March 1995
Pages379–384OBJECTIVE: A number of recent studies have questioned whether, despite modern treatment, the natural course of bipolar illness today still involves multiple relapses and impaired psychosocial functioning. This prospective follow-up study examined ...
https://doi.org/10.1176/ajp.152.3.379Publication date: 01 March 1995
Pages385–390OBJECTIVE: This analysis aimed to quantify the long-term stability of distinctions between nonbipolar, bipolar II, and bipolar I affective disorders and to determine the predictors of shifts in patients' diagnoses among these categories. METHOD: Probands ...
https://doi.org/10.1176/ajp.152.3.385Publication date: 01 March 1995
Pages391–397OBJECTIVE: The authors tested the hypothesis that fluoxetine, when used in combination with relapse prevention psychotherapy, directly reduces relapse frequency and severity for alcoholics. METHOD: The authors conducted a randomized, placebo-controlled ...
https://doi.org/10.1176/ajp.152.3.391Publication date: 01 March 1995
Pages398–403OBJECTIVE: Two smoking cessation studies provided venues to 1) look for differences in affective symptoms between cigarette smokers with and without a history of major depression or other psychiatric diagnoses who were not currently depressed and 2) ...
https://doi.org/10.1176/ajp.152.3.398Publication date: 01 March 1995
Pages404–412OBJECTIVE: The aim of this study was to compare the clinical effects of early-night and late-night partial sleep deprivation in patients with premenstrual dysphoric disorder and normal comparison subjects. METHOD: In the premenstrual phase of two ...
https://doi.org/10.1176/ajp.152.3.404Publication date: 01 March 1995
Pages413–418OBJECTIVE: The purpose of this study was to determine the occurrence of leukopenia and other blood dyscrasias associated with psychiatric use of carbamazepine and valproate. METHOD: Rates of WBC counts of 3,000- 4,000/mm3 (moderate leukopenia) and < 3,000/...
https://doi.org/10.1176/ajp.152.3.413Publication date: 01 March 1995
Pages419–423OBJECTIVE: Several studies suggest that a low cholesterol concentration is associated with a greater than normal risk of mortality from suicide. The authors sought to determine whether a low cholesterol level is associated with a history of serious ...
https://doi.org/10.1176/ajp.152.3.419Publication date: 01 March 1995
Pages424–430OBJECTIVE: The authors investigated the relationship between probands' age at onset of Alzheimer's disease with the risk of primary progressive dementia in the probands' first-degree relatives. METHOD: Two hundred probands with clinically diagnosed ...
https://doi.org/10.1176/ajp.152.3.424Publication date: 01 March 1995
Pages431–435OBJECTIVE: Although well-documented in clinical and epidemiological studies of attention deficit hyperactivity disorder (ADHD) in children, the familial nature of the adult syndrome has not been well investigated. One approach to evaluate the familial ...
https://doi.org/10.1176/ajp.152.3.431Article
Publication date: 01 March 1995
Pages437–440OBJECTIVE: Previous studies have demonstrated a relationship between obsessive-compulsive disorder or behavior and Gilles de la Tourette syndrome. It has been hypothesized that the serotonergic system is implicated in the etiology of obsessive-compulsive ...
https://doi.org/10.1176/ajp.152.3.437Publication date: 01 March 1995
Pages441–443OBJECTIVE: Family accommodation of patients with obsessive-compulsive disorder, i.e., participation in symptoms and modification of personal and family routines, was assessed in relation to family stress, functioning, and attitudes toward the patient. ...
https://doi.org/10.1176/ajp.152.3.441Publication date: 01 March 1995
Pages444–446OBJECTIVE: The authors measured the ratio of N-acetyl aspartate (a putative neuronal marker) to creatine-phosphocreatine in patients with first-episode psychosis by using proton magnetic resonance spectroscopy (MRS). METHOD: Temporal lobe 1H MRS was ...
https://doi.org/10.1176/ajp.152.3.444Publication date: 01 March 1995
Pages447–449OBJECTIVE: This study compared morphometric analyses of brain regions in elderly subjects with early- or late-onset schizophrenia to identify structural abnormalities responsible for schizophrenia. METHOD: Quantitative analyses of magnetic resonance ...
https://doi.org/10.1176/ajp.152.3.447Publication date: 01 March 1995
Pages450–452OBJECTIVE: Studies in Finland, England, and Denmark have reported that individuals exposed to the 1957 A2 influenza pandemic during their second trimester in utero are at greater risk for later schizophrenia. However, other studies in England, the United ...
https://doi.org/10.1176/ajp.152.3.450Publication date: 01 March 1995
Pages453–455OBJECTIVE: The authors sought to determine whether smoking is related to schizophrenia or neuroleptic treatment. METHOD: Cigarette smoking was measured in all patients hospitalized at a state hospital (N = 360) and compared in relation to gender and ...
https://doi.org/10.1176/ajp.152.3.453Publication date: 01 March 1995
Pages456–458OBJECTIVE: The authors sought to determine how substance abuse affects family relationships of persons with severe mental illness. METHOD: Patient reports of family relationships were compared between 101 psychiatric inpatients with a concurrent substance ...
https://doi.org/10.1176/ajp.152.3.456Publication date: 01 March 1995
Pages459–461OBJECTIVE: The authors' goal was to study subtyping, demographic variables, suicidality, diagnostic stability, and 2-year rehospitalization outcome for inpatients given the admission diagnosis of adjustment disorder at their institution. METHOD: They ...
https://doi.org/10.1176/ajp.152.3.459Article
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Publication date: 01 March 1995
Pages481–482The American Psychiatric Association encourages psychiatrists to 1) diagnose and treat nicotine dependence, 2) recognize the possible role of nicotine and underlying neurochemical mechanisms in the understanding, diagnosis, and treatment of psychiatric ...
https://doi.org/10.1176/ajp.152.3.481Publication date: 01 March 1995
Page482This statement was proposed by the Committee on Women1 of the Council on National Affairs. It was approved by the Assembly in November 1994 and by the Board of Trustees in December 1994.
https://doi.org/10.1176/ajp.152.3.482