American Journal of Psychiatry
- Volume 153
- Number 2
- February 1996
Article
Publication date: 01 February 1996
Pages151–162OBJECTIVE: This article describes a paradigm--initiation and adaptation- -within which to conceptualize the drug-induced neural plasticity that underlies the long-term actions of psychotropic drugs in the brain. METHOD: Recent advances in neurobiology are ...
https://doi.org/10.1176/ajp.153.2.151Publication date: 01 February 1996
Pages163–173OBJECTIVE: The purpose of this article is to review the literature concerning gender differences in the course of bipolar illness and discuss issues relevant to the treatment of women with the illness. METHOD: The literature concerning the following ...
https://doi.org/10.1176/ajp.153.2.163Publication date: 01 February 1996
Pages174–182OBJECTIVE: For over 25 years, it has been hypothesized that major depression is due to a deficiency of available serotonin or subsensitivity of key serotonin receptors in relevant brain regions. Direct evidence supporting this hypothesis has been lacking ...
https://doi.org/10.1176/ajp.153.2.174Publication date: 01 February 1996
Pages183–190OBJECTIVE: The purpose of this study was to compare the binding of various typical and atypical neuroleptics to striatal D2 dopamine receptors in schizophrenic patients. METHOD: Fifty-six inpatients with schizophrenia, including 14 with schizoaffective ...
https://doi.org/10.1176/ajp.153.2.183Publication date: 01 February 1996
Pages191–199OBJECTIVE: This study reports the first paired measurements of glucose metabolism and size of thalamic regions in never-medicated schizophrenic patients using coregistered magnetic resonance imaging (MRI) templates. METHOD: Positron emission tomography ...
https://doi.org/10.1176/ajp.153.2.191Publication date: 01 February 1996
Pages200–205OBJECTIVE: This study was undertaken to test the feasibility of using functional magnetic resonance imaging (MRI) to examine changes in cortical activation in response to verbal tasks in two brain regions. METHOD: Twelve schizophrenic patients and 11 ...
https://doi.org/10.1176/ajp.153.2.200Publication date: 01 February 1996
Pages206–212OBJECTIVE: The study addressed the question of whether unsolvable as opposed to solvable cognitive problems activate discrete neuronal systems in the human brain. METHOD: Twelve healthy humans tried to solve unsolvable anagrams. Solvable anagrams and a ...
https://doi.org/10.1176/ajp.153.2.206Publication date: 01 February 1996
Pages213–218OBJECTIVE: The authors compared the health-related quality of life of patients with panic disorder to that of patients with other major chronic medical and psychiatric conditions. METHOD: The physical and mental health of a group of 433 patients with ...
https://doi.org/10.1176/ajp.153.2.213Publication date: 01 February 1996
Pages219–225OBJECTIVE: The aim of this study was to prospectively examine the relationship between immediate and short-term responses to a trauma and the subsequent development of posttraumatic stress disorder (PTSD). METHOD: All patients consecutively admitted to a ...
https://doi.org/10.1176/ajp.153.2.219Publication date: 01 February 1996
Pages226–230OBJECTIVE: This study investigated the hypothesis that following a pregnancy loss, women have more mental health complaints than women who give birth to a living baby. METHOD: Mental health was assessed for 2,140 women during their first trimester of ...
https://doi.org/10.1176/ajp.153.2.226Publication date: 01 February 1996
Pages231–237OBJECTIVE: The purpose of this study was to examine the efficacy and side effects of haloperidol, chlorpromazine, and lorazepam for the treatment of the symptoms of delirium in adult AIDS patients in a randomized, double-blind, comparison trial. METHOD: ...
https://doi.org/10.1176/ajp.153.2.231Publication date: 01 February 1996
Pages238–242OBJECTIVE: This study surveyed HIV-infected patients' attitudes toward physician-assisted suicide and examined the relationship between interest in physician-assisted suicide and physical and psychosocial variables. METHOD: Three hundred seventy-eight ...
https://doi.org/10.1176/ajp.153.2.238Publication date: 01 February 1996
Pages243–247OBJECTIVE: This study explored the relationship between aggressive behavior and other neuropsychiatric symptoms in patients with Alzheimer's disease. METHOD: Consecutively assessed outpatients with probable or possible Alzheimer's disease (N = 75) were ...
https://doi.org/10.1176/ajp.153.2.243Publication date: 01 February 1996
Pages248–255OBJECTIVE: This exploratory study examined the characteristics of a group of unusual and previously undescribed patients with major affective disorder who not only had been continuously symptomatic for prolonged periods of time but were also so ...
https://doi.org/10.1176/ajp.153.2.248Publication date: 01 February 1996
Pages256–260OBJECTIVE: The increasing involvement of insurers and hospitals in monitoring patient care is encroaching on the psychiatrist's autonomy in making clinical decisions. This study examined the prevalence of constraints on psychiatric inpatient practices, as ...
https://doi.org/10.1176/ajp.153.2.256Publication date: 01 February 1996
Pages261–263A 33-year-old pregnant woman at 26 weeks gestation, who had a history of bipolar mood disorder, type I, was admitted to the hospital for hypomania and poorly controlled diabetes mellitus. The patient had had her first episode of affective illness at age ...
https://doi.org/10.1176/ajp.153.2.261Article
Publication date: 01 February 1996
Pages265–267OBJECTIVE: This study examined which characteristics of hallucinations are most likely to change after inpatient treatment. METHOD: Fifty hallucinating psychiatric inpatients were given semistructured interviews shortly after admission and again shortly ...
https://doi.org/10.1176/ajp.153.2.265Publication date: 01 February 1996
Pages268–270OBJECTIVE: Catechol O-methyltransferase (COMT) inactivates catecholamines by methylating their m-hydroxy group. Some previous studies using biochemical methods have found higher levels of COMT activity in schizophrenic patients. Recently, the genetic ...
https://doi.org/10.1176/ajp.153.2.268Article
Publication date: 01 February 1996
Page270In the article "Is Poor Insight in Psychotic Disorders Associated With Poor Performance on the Wisconsin Card Sorting Test?" by Manuel Cuesta, M.D., et al. (September 1995 issue, pp. 1380-1382), the description of awareness of illness was not given. The ...
https://doi.org/10.1176/ajp.153.2.270Publication date: 01 February 1996
Pages271–274OBJECTIVE: This study was undertaken to confirm or refute previous reports that link bipolar affective disorder to polymorphic DNA markers at or near the gene for tyrosine hydroxylase. METHOD: A previous linkage analysis, which used a tetranucleotide ...
https://doi.org/10.1176/ajp.153.2.271Publication date: 01 February 1996
Pages275–277OBJECTIVE: The authors investigated whether histories of childhood physical or sexual abuse were reported more frequently in a clinical sample of patients with anxiety disorders than in a matched community comparison sample. METHOD: A standardized ...
https://doi.org/10.1176/ajp.153.2.275Publication date: 01 February 1996
Pages278–280OBJECTIVE: The authors evaluated features of social anxiety in a group of adult stutterers to explore the soundness of the DSM-IV requirement that social phobia not be diagnosed in patients who stutter if their phobia relates to their stuttering. METHOD: ...
https://doi.org/10.1176/ajp.153.2.278Publication date: 01 February 1996
Pages281–283OBJECTIVE: This study tested the hypothesis that naltrexone reduces relapse rates among alcoholics by modifying the reinforcing effects of initial alcohol consumption and alcohol-induced craving. METHOD: Sixteen alcoholic patients treated with naltrexone ...
https://doi.org/10.1176/ajp.153.2.281Article
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