Focus
- Volume 16
- Number 2
- April 2018
From the Guest Editor
Reviews
Publication date: 01 April 2018
Pages124–134Use of biomarkers to diagnose, predict the prognosis of, and guide the treatment of neuropsychiatric conditions is in its infancy. However, the era of biomarkers is upon us. This article provides an overview of biomarkers, their clinical uses, and ...
https://doi.org/10.1176/appi.focus.20170044Publication date: 01 April 2018
Pages135–142Autism spectrum disorder is still defined and diagnosed behaviorally. Its vast genotypic and phenotypic heterogeneity require a search for biological markers, to develop objective procedures for population-based screening and diagnosis to increase access ...
https://doi.org/10.1176/appi.focus.20170047Publication date: 01 April 2018
Pages143–152The authors give an overview of issues regarding the clinical use of PTSD biomarkers and examine a set of genetic and physiological markers currently proposed as candidate tests for PTSD. They discuss studies that have identified candidate biomarkers with ...
https://doi.org/10.1176/appi.focus.20170045Publication date: 01 April 2018
Pages153–163This article discusses some of the most promising and potentially clinically relevant biomarkers in schizophrenia, with a focus on markers of inflammation, neuroimaging, brain-derived neurotrophic factor, genetic and epigenetic markers, and speech ...
https://doi.org/10.1176/appi.focus.20170046Publication date: 01 April 2018
Pages164–172This article reviews the current evidence base for biomarkers of the most common causes of dementia in later life and benefits the practicing clinician by increasing awareness of the availability and utility of current and emerging biomarkers in dementia ...
https://doi.org/10.1176/appi.focus.20170048Clinical Synthesis
Publication date: 01 April 2018
Pages173–176A case study illustrates the relevance of sleep-related biomarkers to diagnosis, treatment monitoring, and prognosis.
https://doi.org/10.1176/appi.focus.20170040Ask the Expert
Ethics Commentary
Communication Commentary
Applied Armamentarium
Bibliography
Abstracts
Influential Publications
Publication date: 01 April 2018
Pages194–209A plethora of research has implicated hundreds of putative biomarkers for depression, but has not yet fully elucidated their roles in depressive illness or established what is abnormal in which patients and how biologic information can be used to enhance ...
https://doi.org/10.1176/appi.focus.16206Publication date: 01 April 2018
Pages210–218Generalized anxiety disorder (GAD) is a prevalent and highly disabling mental health condition; however, there is still much to learn with regard to pertinent biomarkers, as well as diagnosis, made more difficult by the marked and common overlap of GAD ...
https://doi.org/10.1176/appi.focus.16205Publication date: 01 April 2018
Pages219–224About half of people who take antidepressants do not respond and many experience adverse effects. These detrimental outcomes are in part a result of the impact of an individual's genetic profile on pharmacokinetics and pharmcodynamics. If known and made ...
https://doi.org/10.1176/appi.focus.16204Publication date: 01 April 2018
Pages225–236Objective: Clinical phenomenology remains the primary means for classifying psychoses despite considerable evidence that this method incompletely captures biologically meaningful differentiations. Rather than relying on clinical diagnoses as the gold ...
https://doi.org/10.1176/appi.focus.16207Past Issues
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