The Journal of Neuropsychiatry and Clinical Neurosciences
- Volume 1
- Number 2
- May 1989
Publication date: 01 May 1989
Pages103–125Learning produces changes in neuronal architecture, changes that result from learned alterations in gene expression. Insofar as psychotherapy resembles learning, it is also likely to produce anatomical changes. These changes should be detectable by ...
https://doi.org/10.1176/jnp.1.2.103Publication date: 01 May 1989
Pages128–134Magnetic resonance imaging brain scans were performed on 17 patients with primary affective disorder and 21 normal subjects. A coronal slice through the temporal lobes at the level of the pons and interpeduncular cistern was selected in each subject, and ...
https://doi.org/10.1176/jnp.1.2.128Publication date: 01 May 1989
Pages135–144In a prospective study of depressed elderly patients referred for electroconvulsive therapy (ECT), subcortical white matter hyperintensity (WMH) was seen in all 51 patients 60 years or older who received magnetic resonance imaging (MRI) prior to ...
https://doi.org/10.1176/jnp.1.2.135Publication date: 01 May 1989
Pages145–153Single photon emission computed tomography (SPECT) with [123I]N- isopropyl iodoamphetamine--[123I]IMP--was used to study regional cerebral blood flow (rCBF) in 94 psychiatric patients and six controls. Patients with dementias had distinct brain-image ...
https://doi.org/10.1176/jnp.1.2.145Publication date: 01 May 1989
Pages154–158Intellectual impairment and disease severity tend to parallel one another in patients with Parkinson's disease (PD), but the pattern of development of the neuropsychological impairments contributing to the overall intellectual decline is unknown. This ...
https://doi.org/10.1176/jnp.1.2.154Publication date: 01 May 1989
Pages159–166Four cases of Parkinson's disease with advanced dementia are described. Postmortem examination revealed cell loss in the substantia nigra, with Lewy bodies present, and loss of cells in the basal nucleus of Meynert. A few tangles were observed in the ...
https://doi.org/10.1176/jnp.1.2.159Publication date: 01 May 1989
Pages167–172Increasingly, beta blockers are being utilized to treat patients with aggressive disorders secondary to brain lesions. To secure further data about the potential efficacy of beta blockers for this condition, a rat model was employed in which aggression ...
https://doi.org/10.1176/jnp.1.2.167Publication date: 01 May 1989
Pages173–175A computer-based search was conducted to locate physicians jointly certified by the American Board of Psychiatry and Neurology in both adult psychiatry and adult neurology since 1960. Eighty-six such physicians were found, and a survey concerning their ...
https://doi.org/10.1176/jnp.1.2.173Publication date: 01 May 1989
Pages176–180Sixty-four elderly depressed outpatients were treated with nortriptyline for seven weeks. Plasma nortriptyline and its main metabolite, 10-hydroxynortriptyline, were measured weekly. No relationship was found between levels of 10-hydroxynortriptyline and ...
https://doi.org/10.1176/jnp.1.2.176Publication date: 01 May 1989
Pages181–187Two hundred forty-one nursing home patients from the National Nursing Home Survey Pretest were assessed using the Ischemic Score of Hachinski. Medical chart diagnoses were used to classify those with and without dementia. The Mini-Mental State Examination ...
https://doi.org/10.1176/jnp.1.2.181Publication date: 01 May 1989
Pages188–190Antidepressant-induced delirium in five of 60 (8%) patients over the age of 45 is reported. In each case, delirium developed within two weeks of beginning the antidepressant and appeared to be completely reversible once the medication was discontinued. ...
https://doi.org/10.1176/jnp.1.2.188Publication date: 01 May 1989
Pages190–192Treating psychosis in patients with Parkinson's disease (PD) is one of the more difficult problems in clinical psychiatry. In this case report, a patient with PD and psychosis was treated with the novel neuroleptic clozapine and sustained improvement in ...
https://doi.org/10.1176/jnp.1.2.190Article
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