The Journal of Neuropsychiatry and Clinical Neurosciences
- Volume 1
- Number 3
- August 1989
Publication date: 01 August 1989
Pages225–235The human immunodeficiency virus (HIV), the etiological agent of acquired immunodeficiency syndrome (AIDS), directly affects the central nervous system (CNS) and often causes cognitive, motor, and behavioral changes and eventually a dementia prior to ...
https://doi.org/10.1176/jnp.1.3.225Publication date: 01 August 1989
Pages243–248A consecutive series of 94 patients with Parkinson's disease (PD) were evaluated for the presence of depression and neuropsychological deficits. Patients were divided into groups based on the severity of their PD symptoms and then further subdivided into ...
https://doi.org/10.1176/jnp.1.3.243Publication date: 01 August 1989
Pages249–252Oxiracetam is a recently synthesized nootropic that was tested as a potential treatment for cognitive decline in patients with multi- infarct dementia (MID) and primary degenerative dementia (PDD). Subjects were 34 MID patients and 39 PDD patients who met ...
https://doi.org/10.1176/jnp.1.3.249Publication date: 01 August 1989
Pages253–262The past decade has seen important advances in the clinical utility of serotonergic agents. The putative novel anxiolytic effects of 5-HT1A partial agonists such as buspirone, the antidepressant effects of selective serotonin (5-HT) uptake blockers such ...
https://doi.org/10.1176/jnp.1.3.253Publication date: 01 August 1989
Pages263–268Cognitive performance on the Mini-Mental State Examination (MMSE) was assessed in depressed patients (diagnosis of major depression) with cerebrovascular lesions, with Parkinson's disease, or with functional depression (no known brain lesions). Controls ...
https://doi.org/10.1176/jnp.1.3.263Publication date: 01 August 1989
Pages269–282Positron emission tomography (PET) has dramatically improved our ability to examine the functioning of the living brain. PET studies of neural pathways of the major sensory modalities--auditory, visual, somatosensory--have confirmed many traditional ...
https://doi.org/10.1176/jnp.1.3.269Publication date: 01 August 1989
Pages283–290Evoked potentials of 23 patients with chronic liver disease and delirium were compared with those of matched controls without delirium. Delirious subjects had significantly worse scores on the Mini-Mental State Exam and Trail Making Tests. Mean peak ...
https://doi.org/10.1176/jnp.1.3.283Publication date: 01 August 1989
Pages291–295Levels of dopamine (DA), dihydroxyphenylacetic acid (DOPAC), homovanillic acid (HVA), noradrenaline (NA), 5-hydroxyindoleacetic acid (5-HIAA) in cerebrospinal fluid and serum levels of prolactin (PRL) and dopamine-beta-hydroxylase (DBH) were measured in ...
https://doi.org/10.1176/jnp.1.3.291Publication date: 01 August 1989
Pages296–302Twenty asymptomatic, HIV-seropositive homosexual men and a control group of 20 seronegative homosexual men were evaluated for evidence of neuropsychological impairment. Two-tailed paired t-tests of group differences revealed that the seropositive patients ...
https://doi.org/10.1176/jnp.1.3.296Publication date: 01 August 1989
Pages303–305Reinstitution of antipsychotic medication is problematic in patients with a history of neuroleptic malignant syndrome (NMS). In this case, a patient with a history of probable neuroleptic malignant syndrome caused by administration, as single agents, of ...
https://doi.org/10.1176/jnp.1.3.303Publication date: 01 August 1989
Pages305–307The authors investigated habituation of the eye-blink component of the startle reflex to repeated affectively neutral tactile and auditory stimuli in nine subjects with posttraumatic stress disorder and nine controls. Each group showed rapid habituation ...
https://doi.org/10.1176/jnp.1.3.305