The Journal of Neuropsychiatry and Clinical Neurosciences
- Volume 4
- Number 1
- February 1992
Publication date: 01 February 1992
Pages3–14Studies of aberrations in second messenger function may help to elucidate some of the multiple complex neurobiological alterations in bipolar affective disorders. The phosphatidylinositol and calcium ion (Ca2+) second messengers are of particular interest ...
https://doi.org/10.1176/jnp.4.1.3Publication date: 01 February 1992
Pages15–20In a prospective study to determine the incidence of clinical dementia in patients with AIDS and ARC, 29 men and 3 women, 19 with ARC and 13 with AIDS, were examined neurologically and neuropsychologically every 6 months for 2 years during a placebo-...
https://doi.org/10.1176/jnp.4.1.15Publication date: 01 February 1992
Pages21–28The cognitive and motor deficits associated with human immunodeficiency virus-1 (HIV-1) infection have been studied using neurological examination and neuropsychological tests. However, drug users with HIV- 1 infection generally have been excluded from ...
https://doi.org/10.1176/jnp.4.1.21Publication date: 01 February 1992
Pages29–35Tardive dyskinesia (TD) and drug-induced parkinsonism (DIP) have been hypothesized to reflect opposing states of dopamine (DA) function. In this longitudinal study, 57 psychotic inpatients were rated repeatedly for TD, DIP, and psychosis while receiving ...
https://doi.org/10.1176/jnp.4.1.29Publication date: 01 February 1992
Pages36–41Evidence derived from both pharmacological and postmortem studies suggests that a disturbance of brain iron metabolism is involved in the pathophysiology of schizophrenia; i.e., the distribution of iron parallels that of dopamine, and variations in its ...
https://doi.org/10.1176/jnp.4.1.36Publication date: 01 February 1992
Pages42–44Three patients from different racial, social, and economic backgrounds were studied because of sudden intrusive thoughts: visions or intrusions of threatening scenes--violent, aggressive, and sometimes horrifying--that lasted from seconds to minutes. ...
https://doi.org/10.1176/jnp.4.1.42Publication date: 01 February 1992
Pages45–50The authors present two cases of patients with craniopharyngiomas who meet the DSM-III-R criteria for intermittent explosive disorder. Episodes of rage developed before and/or after surgery for removal of the craniopharyngioma. Magnetic resonance imaging ...
https://doi.org/10.1176/jnp.4.1.45Publication date: 01 February 1992
Pages51–54The HAIR-AN syndrome is characterized by hyperandrogenism, insulin resistance, and acanthosis nigricans. The authors report the first case of an organic mood disorder associated with this condition that improved markedly in response to ovarian suppression ...
https://doi.org/10.1176/jnp.4.1.51Publication date: 01 February 1992
Pages59–63Post-traumatic stress disorder (PTSD) may be associated with changes in endogenous opioid peptide function. To test this hypothesis, 10 male Vietnam combat veterans with PTSD and 8 age-matched male controls underwent a standard grade-incremented exercise ...
https://doi.org/10.1176/jnp.4.1.59Publication date: 01 February 1992
Pages64–69This study examined naming abilities in three groups of older adults with: I) major depression alone, II) major depression with reversible cognitive dysfunction, and III) dementia with depression. Groups I and II differed significantly from dementia ...
https://doi.org/10.1176/jnp.4.1.64Publication date: 01 February 1992
Pages70–75In a preliminary trial, five oral-clomipramine-refractory patients with obsessive-compulsive disorder (OCD) were treated openly with 14 intravenous clomipramine infusions each. Using standardized assessments, three patients were rated as much improved, ...
https://doi.org/10.1176/jnp.4.1.70Publication date: 01 February 1992
Pages76–81This retrospective single-case study demonstrates the development of tolerance and reresponse to carbamazepine in a patient with coexisting trigeminal neuralgia and manic-depressive illness. After an initial positive response, tolerance to the ...
https://doi.org/10.1176/jnp.4.1.76Publication date: 01 February 1992
Pages82–84The effects of buspirone and verapamil on spasmodic torticollis were investigated in two double-blind, placebo-controlled crossover studies. Buspirone was given in doses of 20-100 mg/day for 4 weeks to 14 patients; verapamil was given in doses of 40-100 ...
https://doi.org/10.1176/jnp.4.1.82Publication date: 01 February 1992
Pages85–94Assessments of higher cortical functioning are often neglected in patients with possible coarse neurobehavioral psychiatric disease, such as dementia, stroke, or focal cerebral lesions. When performed, the short Folstein Mini-Mental State Exam (MMSE) is ...
https://doi.org/10.1176/jnp.4.1.85Publication date: 01 February 1992
Pages95–98Our previous article showed that the discriminating properties of most diagnostic tests in medicine can be characterized by assuming that tests separate disordered and nondisordered individuals into two overlapping, normal distributions with different ...
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