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The Journal of Neuropsychiatry and Clinical Neurosciences

  • Volume 4
  • Number 2
  • May 1992

Publication date: 01 May 1992

Pages125–133

Fundamental problems in the analysis of functional and structural imaging data include data transport, boundary identification (including manual tracing, edge detection, and tissue segmentation), volume estimation, three-dimensional reconstruction and ...

https://doi.org/10.1176/jnp.4.2.125

Publication date: 01 May 1992

Pages134–139

The authors examined a consecutive series of 50 patients for the presence of apathy, depression, anxiety, and neuropsychological deficits using a neuropsychological battery that included a recently designed apathy scale. This scale was found to be ...

https://doi.org/10.1176/jnp.4.2.134

Publication date: 01 May 1992

Pages140–144

Medical records were retrospectively reviewed for 20 medically ill geriatric patients who received electroconvulsive therapy (ECT) for post-stroke depression from January 1982 to January 1991 at Massachusetts General Hospital. Of the 19 patients (95%) who ...

https://doi.org/10.1176/jnp.4.2.140

Publication date: 01 May 1992

Pages145–151

Electroconvulsive therapy (ECT) has been used effectively in treating depressed patients with multiple sclerosis (MS). However, several reports have observed that some patients with MS may suffer neurological deterioration during ECT. The authors describe ...

https://doi.org/10.1176/jnp.4.2.145

Publication date: 01 May 1992

Pages152–158

The authors examined whether specific neuropsychological abnormalities in multiple sclerosis (MS) are associated with focal lesion areas detected by MRI. Lesion area, regardless of distribution, correlated with performance on the vast majority of ...

https://doi.org/10.1176/jnp.4.2.152

Publication date: 01 May 1992

Pages159–167

Localized cerebral utilization rates for glucose (CMRglu) were determined in 10 detoxified patients with alcoholic organic mental disorders and in 7 age-equivalent normal volunteers using [18F]2-fluoro- 2-deoxyglucose positron emission tomography. ...

https://doi.org/10.1176/jnp.4.2.159

Publication date: 01 May 1992

Pages168–173

Immunocytochemical staining for glial fibrillary acidic protein (GFAP) allows more specific identification of astrocytes and their processes than classical histochemical techniques and has therefore recently been used by some investigators to quantify ...

https://doi.org/10.1176/jnp.4.2.168

Publication date: 01 May 1992

Pages174–178

Previous studies of the frequency of high-signal lesions in human immunodeficiency virus (HIV) infection have had methodological weaknesses regarding lack of control groups, differing machine strengths, and biased subject selection. To obtain a more ...

https://doi.org/10.1176/jnp.4.2.174

Publication date: 01 May 1992

Pages179–184

The Folstein Mini-Mental State Examination (MMSE) and dementia screening measures developed by Benton (temporal orientation, oral word association, and visual reconstruction tasks) were compared for diagnostic efficacy with geriatric inpatients ...

https://doi.org/10.1176/jnp.4.2.179

Publication date: 01 May 1992

Pages185–187

A case of neuroleptic malignant syndrome (NMS) is described in a congenitally brain-damaged deaf patient. The literature suggests that NMS in patients with organic brain syndrome is induced by a reduction of marginal stores of dopamine in the hypothalamus ...

https://doi.org/10.1176/jnp.4.2.185

Publication date: 01 May 1992

Pages187–189

Depressive symptoms were rated during a double-blind placebo-controlled trial of nadolol for chronic aggression. Depressive symptoms were not significantly different in nadolol and placebo groups during any phase of the drug trial.

https://doi.org/10.1176/jnp.4.2.187

Publication date: 01 May 1992

Pages189–194

The authors report four instances of significant, essentially unprovoked aggressive behavior, including two homicides, following exposure to cholinesterase inhibitors. No subject had a history of violent behavior, antisocial personality, or major ...

https://doi.org/10.1176/jnp.4.2.189

Publication date: 01 May 1992

Pages195–197

The authors report two patients with prolonged metabolic delirium presumably initiated by systemic absorption of homatropine from a topical ophthalmologic solution. Anticholinergic toxicity was confirmed by muscarinic radioreceptor assay in both cases and ...

https://doi.org/10.1176/jnp.4.2.195

Publication date: 01 May 1992

Pages214–219

We continue our examination of diagnostic tests that are used to assign individuals to one of two mutually exclusive categories, those having or not having a particular disorder. Our last article showed how the information yielded by a test depends on the ...

https://doi.org/10.1176/jnp.4.2.214

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