The Journal of Neuropsychiatry and Clinical Neurosciences
- Volume 4
- Number 3
- August 1992
Publication date: 01 August 1992
Pages239–248Prior studies of patients with dementia have found similar qualitative patterns of cerebral glucose utilization with [18F]2-fluoro-2- deoxyglucose (FDG) PET and of putative muscarinic receptor activity with [123I]3-quinuclidinyl-4-iodobenzilate (IQNB). ...
https://doi.org/10.1176/jnp.4.3.239Publication date: 01 August 1992
Pages249–256Rapid eye movement (REM) sleep measures distinguish elderly patients with depression from those with dementia. The authors used a 2-night REM sleep deprivation (RSD) protocol to characterize patients with mixed symptoms of depression and dementia in ...
https://doi.org/10.1176/jnp.4.3.249Publication date: 01 August 1992
Pages257–264Significant anxiety in combination with depression may represent a specific depressive subtype in Parkinson's disease (PD). To ascertain the prevalence of this symptom complex, we administered a self-report survey and standardized psychological tests that ...
https://doi.org/10.1176/jnp.4.3.257Publication date: 01 August 1992
Pages265–269A study of 34 hospitalized patients with suspected neuroleptic malignant syndrome (NMS) found that 24 had NMS and the other 10 had acute, usually serious, medical problems. There were no demographic, psychopathologic, or treatment-related differences ...
https://doi.org/10.1176/jnp.4.3.265Publication date: 01 August 1992
Pages270–279Neuropsychological functioning and cerebrospinal fluid concentrations of an endogenous neurotoxin, quinolinic acid (QUIN) were evaluated in 52 HIV-positive individuals (71% without constitutional symptoms) and 33 HIV-seronegative controls (including 15 ...
https://doi.org/10.1176/jnp.4.3.270Publication date: 01 August 1992
Pages280–287Positron-emission tomography was coupled with neurological and neuropsychological evaluation to study regional cerebral activity and neurologic status in two groups. Seventeen patients with full-blown AIDS and 14 seronegative control subjects were studied ...
https://doi.org/10.1176/jnp.4.3.280Publication date: 01 August 1992
Pages288–293In a preliminary study, 30 nondemented human immunodeficiency virus (HIV-1) seropositive subjects without acquired immunodeficiency syndrome and 14 seronegative controls performed a reaction time measure of spatial attention. Compared with controls, ...
https://doi.org/10.1176/jnp.4.3.288Publication date: 01 August 1992
Pages294–302Features of event-related potentials (ERPs) may be sensitive and clinically useful markers of central nervous system infection by the human immunodeficiency virus (HIV-1); however, this application has not been studied in the risk group of intravenous ...
https://doi.org/10.1176/jnp.4.3.294Publication date: 01 August 1992
Pages303–307ALZ50-based enzyme immunoassay was used to study distribution of Alzheimer's disease-associated protein (ADAP) in postmortem brain tissues of 5 Alzheimer's disease (AD) and 5 non-Alzheimer's disease (NAD) subjects. There are at least three AD-associated ...
https://doi.org/10.1176/jnp.4.3.303Publication date: 01 August 1992
Pages308–314A group of 125 healthy young adults was given a memory battery 1 hour after administration of alprazolam (0.5 and 1.0 mg), buspirone (5 and 10 mg), and placebo under single-dose, double-blind conditions. On the wordlist recall battery and a 24-hour retest,...
https://doi.org/10.1176/jnp.4.3.308Publication date: 01 August 1992
Pages315–319A 10-year-old girl with intractable complex partial seizures developed aphasia, coprolalia, and repetitive motor behaviors involving touching, sexual touching, and aggressive acts. Her symptoms subsided following surgical resection of a left anterior ...
https://doi.org/10.1176/jnp.4.3.315Publication date: 01 August 1992
Pages331–335In our last two articles, we showed that one can quantify the reduction in uncertainty that results from diagnostic testing, an insight that allowed us to describe a method for optimizing the performance of a test by choosing a cutoff that maximizes its ...
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