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The Journal of Neuropsychiatry and Clinical Neurosciences

  • Volume 5
  • Number 3
  • August 1993

Publication date: 01 August 1993

Pages241–253

Recent data from studies of the prefrontal cortex (PFC) in humans and laboratory animals are reviewed with particular reference to the anatomical substrates of prefrontal neuropsychological function in health and disease. The PFC has been shown to have a ...

https://doi.org/10.1176/jnp.5.3.241

Publication date: 01 August 1993

Pages254–259

The effect of drug and alcohol abuse on neuropsychological performance was examined in 132 human immunodeficiency virus-seropositive gay or bisexual men. Syndromal (diagnostic) criteria of alcohol/drug abuse based on DSM-III-R were used, and quantitative ...

https://doi.org/10.1176/jnp.5.3.254

Publication date: 01 August 1993

Pages277–282

The authors examined differences between the verbal memory performance of older patients with major depression (MD) alone; major depression with reversible depression-related cognitive dysfunction (MD/DRCD); and primary dementia and major depression (DEM/...

https://doi.org/10.1176/jnp.5.3.277

Publication date: 01 August 1993

Pages283–286

Among epileptic patients, personality disorders may be associated with specific seizure manifestations. In an epilepsy clinic, we identified 42 idiopathic epilepsy patients diagnosed with various DSM-III-R personality disorders, including borderline, ...

https://doi.org/10.1176/jnp.5.3.283

Publication date: 01 August 1993

Pages287–293

To investigate a possible association of midline cerebral malformations with psychotic disorders, MRI and CT scans were blindly evaluated for 52 patients with schizophrenia, 9 with schizoaffective disease, and 79 consecutive nonpsychotic control subjects. ...

https://doi.org/10.1176/jnp.5.3.287

Publication date: 01 August 1993

Pages294–300

Previous research on persons with schizophrenia and their relatives suggests two independent etiologic factors may combine to produce schizophrenia, and these factors may be indexed respectively by independent neuropsychological tests. Two neurocognitive ...

https://doi.org/10.1176/jnp.5.3.294

Publication date: 01 August 1993

Pages301–306

The authors investigated the hypothesis that early abuse might affect the development of the limbic system. During initial psychiatric evaluation, 253 outpatients completed a self-report scale, the Limbic System Checklist-33 (LSCL-33), designed to measure ...

https://doi.org/10.1176/jnp.5.3.301

Publication date: 01 August 1993

Pages307–315

Fifteen children with autism were treated with 60 mg d,l-fenfluramine (FEN) or placebo in a double-blind A-B-A protocol followed immediately by double-blind placebo-controlled crossover administration of FEN (total duration 62 weeks). Both biochemical and ...

https://doi.org/10.1176/jnp.5.3.307

Publication date: 01 August 1993

Pages316–321

The authors studied the relationship between cerebral metabolism and brain electrical activity in patients with acquired immunodeficiency syndrome (AIDS), using positron-emission tomography and quantitative electroencephalography. Electroencephalographic ...

https://doi.org/10.1176/jnp.5.3.316

Publication date: 01 August 1993

Pages322–329

Data on 22 subjects treated with fluoxetine suggest that magnetic resonance spectroscopy (MRS) of fluorine-19 can measure brain concentrations of fluoxetine/norfluoxetine in vivo. Fluoxetine accumulates in the human brain relative to plasma, with brain ...

https://doi.org/10.1176/jnp.5.3.322

Publication date: 01 August 1993

Pages330–334

A sample of 133 candidates for antidepressant or mood-stabilizing medication treatment, with acute onset or a new phase of illness between the autumnal and vernal equinoxes, was gathered over a 3-year period from a private outpatient practice. All ...

https://doi.org/10.1176/jnp.5.3.330

Publication date: 01 August 1993

Pages335–337

In a study of 45 patients with anxiety disorders and 11 control subjects, mean cerebrospinal fluid (CSF) concentrations of thyrotropin- releasing hormone (TRH) were not significantly different between nonpsychiatric control subjects and those with panic ...

https://doi.org/10.1176/jnp.5.3.335

Publication date: 01 August 1993

Pages337–341

The authors examined the brain magnetic resonance imaging scans of two epilepsy patients who had temporal lobectomies, one on the right and one on the left, with postoperative symptoms of affective disorders. Degenerative changes of ipsilateral thalamus ...

https://doi.org/10.1176/jnp.5.3.337

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