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The Journal of Neuropsychiatry and Clinical Neurosciences

  • Volume 5
  • Number 4
  • November 1993

Publication date: 01 November 1993

Pages361–368

Recent experimental work suggests involvement of the phosphatidyl inositol second messenger system in the biochemical mechanism of lithium action, but this work has not shed light on the pathophysiology of bipolar illness. Earlier work had established ...

https://doi.org/10.1176/jnp.5.4.361

Publication date: 01 November 1993

Pages369–374

The frequency, course, and clinical correlates of generalized anxiety disorder (GAD) and its relationship to major depression were examined in 66 patients with traumatic brain injury (TBI). Of 66 TBI patients, 7 (11%) had both GAD and major depression; 10 ...

https://doi.org/10.1176/jnp.5.4.369

Publication date: 01 November 1993

Pages375–378

Many of the structural brain abnormalities found in schizophrenia (SC) and bipolar disorder (BD) over the past decade are believed to represent impaired neurodevelopmental processes. The authors hypothesized that incidental developmental anomalies would ...

https://doi.org/10.1176/jnp.5.4.375

Publication date: 01 November 1993

Pages379–383

Five patients with a manic episode and 7 age-comparable control subjects were studied with single-photon emission computed tomography and [99mTc]d,l-hexamethylpropyleneamine oxime. Manic patients showed significantly lower blood flow in the basal portion ...

https://doi.org/10.1176/jnp.5.4.379

Publication date: 01 November 1993

Pages384–394

The functional neuroanatomy of emotion recognition is inadequately understood despite well-documented clinical situations where emotion recognition is impaired (aprosodia). Oxygen-15 water positron-emission tomography (PET) was used to study 9 healthy ...

https://doi.org/10.1176/jnp.5.4.384

Publication date: 01 November 1993

Pages395–400

Cortical serotonin receptor binding was measured with positron-emission tomography (PET) in uninjured regions of cortex in 26 stroke patients. Cognitive function was assessed with the Mini-Mental State Exam (MMSE) and a neuropsychological test battery. ...

https://doi.org/10.1176/jnp.5.4.395

Publication date: 01 November 1993

Pages401–408

This retrospective study examined the association between abuse history and neurological abnormalities in 115 consecutive patients admitted to a child and adolescent psychiatric inpatient unit. Increased electrophysiological abnormalities were found in ...

https://doi.org/10.1176/jnp.5.4.401

Publication date: 01 November 1993

Pages409–414

Computerized EEG activity derived from the temporal lobes was investigated in normal subjects and panic disorder patients with and without depersonalization and/or derealization, in a resting condition and during an odor stimulation task. Panic patients ...

https://doi.org/10.1176/jnp.5.4.409

Publication date: 01 November 1993

Pages415–418

A study of 76 consecutive xenon-133 SPECT studies of regional cerebral blood flow was undertaken to determine the frequency of various patterns of blood flow in cases of clinically diagnosed probable and possible Alzheimer's disease. The reference ...

https://doi.org/10.1176/jnp.5.4.415

Publication date: 01 November 1993

Pages419–427

Research indicates that cocaine significantly constricts the cerebral vasculature and can lead to ischemic brain infarction. Long-term effects of intermittent or casual cocaine use in patients without symptoms of stroke or transient ischemic attack were ...

https://doi.org/10.1176/jnp.5.4.419

Publication date: 01 November 1993

Pages428–430

Electroconvulsive therapy (ECT) was used to treat a patient with a large left frontal craniotomy and remaining frontal meningioma. Treatment was successful and uneventful. ECT should be considered in the treatment of drug-resistant depressed patients with ...

https://doi.org/10.1176/jnp.5.4.428

Publication date: 01 November 1993

Pages430–434

A retrospective chart review identified 11 patients with type 1 human immunodeficiency virus (HIV) who presented to an HIV/AIDS psychiatric service with an acute manic episode. Demographic data, neurodiagnostic studies, and treatment results are ...

https://doi.org/10.1176/jnp.5.4.430

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