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The Journal of Neuropsychiatry and Clinical Neurosciences

  • Volume 9
  • Number 1
  • February 1997

Publication date: 01 February 1997

Pages1–17

The concept of "balanced serotonergic/dopaminergic antagonists" reflects renewed interest in the role of serotonin (5-HT) in schizophrenia. Postmortem brain tissue analysis, cerebrospinal fluid studies, and pharmacological challenges suggest a deficit in ...

https://doi.org/10.1176/jnp.9.1.1

Publication date: 01 February 1997

Pages18–22

Frequency of DSM-III-R posttraumatic stress disorder (PTSD) was studied in 47 active-duty service members (46 male, 1 female; mean age 27 = 7) with moderate traumatic brain injury and neurogenic amnesia for the event. Patients had attained "oriented and ...

https://doi.org/10.1176/jnp.9.1.18

Publication date: 01 February 1997

Pages23–28

In response to ongoing complaints of memory, attention, and problem- solving difficulties among veterans of Operation Desert Storm and Shield (ODSS), a sample of 44 male veterans of ODSS underwent a comprehensive neuropsychological evaluation. Deficits ...

https://doi.org/10.1176/jnp.9.1.23

Publication date: 01 February 1997

Pages29–36

Other investigators have reported clinical improvement from psychostimulant drugs in patients with HIV-1-related cognitive impairment. However, no previous research has substantiated this claim by using a controlled study design. We examined the efficacy ...

https://doi.org/10.1176/jnp.9.1.29

Publication date: 01 February 1997

Pages37–44

The relationship of self-reported cognitive, motor, and affective complaints to actual neuropsychological functioning was explored in a cohort of predominantly symptomatic HIV-1 seropositive individuals. Ninety-two symptomatic HIV-1 infected subjects were ...

https://doi.org/10.1176/jnp.9.1.37

Publication date: 01 February 1997

Pages45–54

Thirteen asymptomatic HIV-infected (HIV+) and 13 healthy control (HIV-) subjects were instructed to detect "oddball" target tones from among a sequence of nontarget tones delivered rapidly (3 tones/second) in one ear while ignoring a similar sequence ...

https://doi.org/10.1176/jnp.9.1.45

Publication date: 01 February 1997

Pages55–63

Functional neuroimaging studies have found abnormal anterior cingulate activity in depressed subjects, and other studies have shown that the cingulate gyrus becomes active in healthy subjects during interference tasks. The authors hypothesized that ...

https://doi.org/10.1176/jnp.9.1.55

Publication date: 01 February 1997

Pages64–67

The apolipoprotein E (APOE) locus on chromosome 19 has been shown to modify risk, and age at onset, of Alzheimer's disease (AD). The authors hypothesized that the phenotypic expression of different psychiatric symptoms in patients with AD would be ...

https://doi.org/10.1176/jnp.9.1.64

Publication date: 01 February 1997

Pages68–74

Thirty-nine patients with probable Alzheimer's disease (AD) were studied with [99mTc]HMPAO SPECT and a standardized neuropsychological battery testing intellect, memory, attention, language, motor and praxis functions, and depression. Spearman rank ...

https://doi.org/10.1176/jnp.9.1.68

Publication date: 01 February 1997

Pages75–80

Plasma gamma-aminobutyric acid (GABA) levels were measured in 14 subjects with Prader-Willi syndrome, 9 subjects with Angelman syndrome, and matched control subjects. Mean levels in both patient groups were 2 to 3 times higher than in nonretarded ...

https://doi.org/10.1176/jnp.9.1.75

Publication date: 01 February 1997

Pages81–89

Forty-six schizophrenic, 22 bipolar, and 26 normal control subjects were administered negative and positive symptoms scales and tests of cognitive function. Test performance was related to diagnosis and to positive and negative symptom ratings within the ...

https://doi.org/10.1176/jnp.9.1.81

Publication date: 01 February 1997

Pages91–93

The visual scanning of 19 recently abstinent crack cocaine-dependent men was assessed while they viewed a picture of a cocaine cue and a picture of a neutral cue. Cocaine craving scores were inversely correlated with the number of preattentive fixations ...

https://doi.org/10.1176/jnp.9.1.91

Publication date: 01 February 1997

Pages94–98

A comprehensive neuropsychological test battery was administered to 3 patients who met the clinical criteria of corticobasal degeneration (CBD). The pattern of neuropsychological deficits in CBD appears to be a distinctive mixture of posterior cortical ...

https://doi.org/10.1176/jnp.9.1.94

Publication date: 01 February 1997

Pages99–101

The authors report 2 clinical cases that illustrate the difficulties with video-monitored EEG and the advantages of brain SPECT in differential diagnosis of true epileptic seizures and nonepileptic seizures. Injection of [99mTc]HMPAO at the time of the ...

https://doi.org/10.1176/jnp.9.1.99

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