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The Journal of Neuropsychiatry and Clinical Neurosciences

  • Volume 9
  • Number 4
  • November 1997

Publication date: 01 November 1997

Pages525–533

The sensitization model of mood disorders, articulated 10 years ago, predicts symptoms, course, and treatment response relationships. However, clinical data testing this model have not been reviewed. The authors reviewed all English-language publications ...

https://doi.org/10.1176/jnp.9.4.525

Publication date: 01 November 1997

Pages534–540

Acute disseminated encephalomyelitis is a disorder associated with significant morbidity and mortality. A description and literature review are presented to focus attention on the myriad neuropsychiatric manifestations of this disease. Common psychiatric ...

https://doi.org/10.1176/jnp.9.4.534

Publication date: 01 November 1997

Pages541–548

Two studies tested the reliability and validity of the Overt Agitation Severity Scale (OASS), a new instrument developed to define and objectively rate the severity of agitated behavior. The authors postulate that agitation should be conceptualized as ...

https://doi.org/10.1176/jnp.9.4.541

Publication date: 01 November 1997

Pages549–555

The goals of this study were to examine the relationship between community violence and inpatient assaults and to identify neurological and neuropsychological deficits underlying violent behavior. Thirty- three inpatients with a history of community ...

https://doi.org/10.1176/jnp.9.4.549

Publication date: 01 November 1997

Pages556–561

One hundred nine outpatients with Alzheimer's disease (AD) were neuropsychiatrically evaluated and rated on standardized measures of depression, activities of daily living (ADL), nonmood behavioral disturbance, and burdensome events such as serious ...

https://doi.org/10.1176/jnp.9.4.556

Publication date: 01 November 1997

Pages562–567

Previous studies suggest that many untreated schizophrenia patients exhibit motor disturbances. On the basis of these findings, the authors hypothesized that preexisting extrapyramidal movement disorders may increase the risk of developing neuroleptic-...

https://doi.org/10.1176/jnp.9.4.562

Publication date: 01 November 1997

Pages568–573

Positron emission tomography was employed to contrast the brain activation pattern in patients with obsessive-compulsive disorder (OCD) to that of matched control subjects while they performed an implicit learning task. Although patients and control ...

https://doi.org/10.1176/jnp.9.4.568

Publication date: 01 November 1997

Pages574–578

The authors studied the relationship between brain metabolic activity and quantitative electroencephalographic power in AIDS. Basal ganglia and thalamic metabolic activity, measured with positron emission tomography, correlated positively with EEG power ...

https://doi.org/10.1176/jnp.9.4.574

Publication date: 01 November 1997

Pages579–583

The authors retrospectively reviewed the charts of 29 inpatients with AIDS and 24 medically ill inpatients, all of whom were exposed to neuroleptics. Results adjusted for age, gender, type and dosage of neuroleptic, and extrapyramidal prophylaxis ...

https://doi.org/10.1176/jnp.9.4.579

Publication date: 01 November 1997

Pages584–590

This study examined age-related differences and correlates of deficits on phonological and category fluency tasks performed by schizophrenic patients. Equal numbers (n = 41) of geriatric (age > 64) and nongeriatric chronically hospitalized schizophrenic ...

https://doi.org/10.1176/jnp.9.4.584

Publication date: 01 November 1997

Pages591–593

This pilot study compared haloperidol, fluoxetine, and placebo for reduction of agitation in 15 outpatients with AD. The two drugs were no more effective than placebo at reducing agitation in these subjects; however, both drugs produced more toxicity than ...

https://doi.org/10.1176/jnp.9.4.591

Publication date: 01 November 1997

Pages594–597

This pilot study investigated effectiveness and tolerability of risperidone for the treatment of psychosis and agitation in 9 inpatients with Parkinson's disease and dementia. Investigators found risperidone to be effective and safe, without worsening ...

https://doi.org/10.1176/jnp.9.4.594

Publication date: 01 November 1997

Pages598–600

Odor identification was assessed in 20 Huntington's disease (HD) patients, 20 normal adults with the genetic mutation that causes HD, and 20 mutation-negative adults. The University of Pennsylvania Smell Identification Test (UPSIT) revealed substantial ...

https://doi.org/10.1176/jnp.9.4.598

Article

Publication date: 01 November 1997

Pages606-a–620

The behavioral effects of the removal of both temporal lobes, including the uncus and the greater part of the hippocampus, were studied in macaques. The monkeys exhibited the following symptoms: 1) forms of behavior which seem to be indicative of "psychic ...

https://doi.org/10.1176/jnp.9.4.606-a

Article

Article

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