The Journal of Neuropsychiatry and Clinical Neurosciences
- Volume 10
- Number 1
- February 1998
Special Article
Publication date: 01 February 1998
Pages1–9Neuropsychiatric research seeks to improve the lives of patients with brain-based behavioral disturbances. There has been dramatic progress in diagnosis and treatment of neuropsychiatric disorders, and progress in neuroscience and biotechnology promises ...
https://doi.org/10.1176/jnp.10.1.1Publication date: 01 February 1998
Pages10–19Tay-Sachs disease (a GM2 gangliosidosis) is an inherited neuronal storage disease that can affect individuals across the age spectrum. Psychosis is reported in 30% to 50% of adult-onset patients, and many are misdiagnosed with schizophrenia. Mood ...
https://doi.org/10.1176/jnp.10.1.10Regular Article
Publication date: 01 February 1998
Pages20–25Rapid-rate transcranial magnetic stimulation (rTMS) allows for the noninvasive examination of the cerebral cortex. Recent studies have begun to investigate whether rTMS may be therapeutic for the treatment of depression. In the present study, the authors ...
https://doi.org/10.1176/jnp.10.1.20Publication date: 01 February 1998
Pages26–33To examine the independent association of depression following acute stroke with impairment in activities of daily living (ADL), the authors conducted a cross-sectional analysis of stroke patients enrolled in the Stroke Data Bank (U.S.A.) who had ...
https://doi.org/10.1176/jnp.10.1.26Publication date: 01 February 1998
Pages34–40The effect of anxiety disorder on recovery from impairment following stroke was examined in 142 patients with acute stroke who had follow-up evaluations. Anxiety disorder significantly interacted with depression to influence the severity and course of ...
https://doi.org/10.1176/jnp.10.1.34Publication date: 01 February 1998
Pages41–47In stroke and other medical illnesses, secondary depression may be associated with different factors in women than in men. The authors examined 301 consecutive admissions for acute treatment of cerebrovascular accident for gender differences in depression,...
https://doi.org/10.1176/jnp.10.1.41Publication date: 01 February 1998
Pages48–54Disagreement remains as to whether drug use can result in an autonomous psychotic disorder. If drug use can create new psychosis cases, an increase in the number of psychosis patients ought to be observable following periods of increased drug use by the ...
https://doi.org/10.1176/jnp.10.1.48Publication date: 01 February 1998
Pages55–63Neuropsychiatric symptom responses to tacrine were investigated in an open-label study of Alzheimer's outpatients. Forty subjects were stratified into three groups (Mild, Moderate, and Severe) based on Mini-Mental State Examination scores. A significant ...
https://doi.org/10.1176/jnp.10.1.55Publication date: 01 February 1998
Pages64–67This study tested the hypothesis that olfactory dysfunction could discriminate between groups of patients with Alzheimer's disease and major depression. Forty patients meeting DSM-IV criteria for Alzheimer's disease and for major depression (20 per group) ...
https://doi.org/10.1176/jnp.10.1.64Publication date: 01 February 1998
Pages68–77Extrapyramidal symptoms (EPS) occur more frequently in dementia of the Alzheimer's type (DAT) than in normal aging. Other late-life mental disorders, however, have also been associated with EPS. To examine whether EPS are increased in DAT patients ...
https://doi.org/10.1176/jnp.10.1.68Publication date: 01 February 1998
Pages78–84A defective blood–brain barrier (BBB) has been postulated to be present in Alzheimer's disease (AD), which would allow circulating β-amyloid peptide to enter the brain. The authors tested this hypothesis by studying BBB function in 14 individuals with ...
https://doi.org/10.1176/jnp.10.1.78Publication date: 01 February 1998
Pages85–92Increasing recognition of the neurologic aspects of depressive disorder has aroused new interest in the potential neuropathologic significance of “psychomotor” symptoms in depression. Psychomotor symptoms have yet to be clearly defined, however. The Motor ...
https://doi.org/10.1176/jnp.10.1.85Clinical and Research Report
Publication date: 01 February 1998
Pages93–95The cost, side effect profile, and required weekly blood draws associated with clozapine may dissuade some clinicians from prescribing this atypical neuroleptic to mentally retarded patients. All publications on clozapine use in mentally retarded patients ...
https://doi.org/10.1176/jnp.10.1.93Publication date: 01 February 1998
Pages96–99A number of disorders characterized by intrusive repetitive symptoms and varying degrees of insight may overlap phenomenologically and neurobiologically with obsessive-compulsive disorder (OCD). There is a question as to whether olfactory reference ...
https://doi.org/10.1176/jnp.10.1.96Publication date: 01 February 1998
Pages100–102The authors examined the prevalence of Alzheimer's disease and apolipoprotein E allele frequencies in the Old Order Amish. A lower frequency of dementia in the Amish does not appear to be due to a reduced E4 frequency.
https://doi.org/10.1176/jnp.10.1.100Neuropsychiatric Practice and Opinion
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