Trazodone in depressed outpatients

Publication: American Journal of Psychiatry

https://doi.org/10.1176/ajp.139.6.803

Abstract

The authors compared the nontricyclic antidepressant trazodone with amitriptyline and placebo in a double-blind study of 202 unipolar depressed outpatients. Trazodone's clinical efficacy was similar to that of amitriptyline, with both active drugs producing significantly more clinical improvement than placebo. The incidence of anticholinergic side effects was lower for the patients taking trazodone than for those taking amitriptyline.

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Information & Authors

Information

Published In

American Journal of Psychiatry

Volume 139 • Number 6 • June 1982

Pages: 803 - 806

PubMed: 7044154

History

Published in print: June 1982

Published online: 1 April 2006

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Trazodone in depressed outpatients

Abstract

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